{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:29:23Z","timestamp":1786649363308,"version":"build-2736575974"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T00:00:00Z","timestamp":1753142400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Perforation peritonitis remains a significant cause of morbidity and mortality in emergency surgical patients. Conventionally, open laparotomy has been the preferred approach. However, with advancements in minimally invasive techniques, laparoscopic management has emerged as a potential alternative. The study aims to assess the feasibility and effectiveness of laparoscopic surgery compared to open laparotomy in managing perforation peritonitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods:<\/jats:title>\n                    <jats:p>A prospective observational study was conducted from January 2022 to May 2023 for patients diagnosed with perforation peritonitis. A total of 140 patients were recruited, 110 patients underwent laparotomy while 30 patients underwent laparoscopic management. Propensity score matching (PSM) in 1:1 ratio was applied to balance confounding variables, resulting in two matched groups of 28 patients each. Operative time, length of post-operative stay, post-operative Visual Analogue Scale score, morbidity and mortality rates were compared.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The mean operative time was significantly longer in the laparoscopic group (217.43 \u00b1 86.10 min) compared to the laparotomy group (182.46 \u00b1 31.63 min;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.049). However, patients in the laparoscopic group experienced a significantly shorter hospital stay (4.39 \u00b1 2.04 days vs. 8.68 \u00b1 3.45 days;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001) and lower post-operative pain scores at all time points (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.012). The 30-day morbidity rate was lower in the laparoscopic group (10% vs. 32%), with fewer surgical site infections and reoperations.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Laparoscopy is a feasible and effective alternative to laparotomy in selected cases of perforation peritonitis, offering benefits such as reduced post-operative pain and shorter hospital stay. Despite technical challenges, improved surgical expertise and patient selection can enhance its role in emergency surgical settings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jmas.jmas_135_25","type":"journal-article","created":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T14:00:07Z","timestamp":1753192807000},"page":"180-186","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Feasibility and outcomes of laparoscopic management in perforation peritonitis: A prospective cohort study with propensity score matching"],"prefix":"10.4103","volume":"22","author":[{"given":"Shruti","family":"Soni","sequence":"first","affiliation":[{"name":"Department of General Surgery, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yash Kumar","family":"Parihar","sequence":"additional","affiliation":[{"name":"Department of General Surgery, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramkaran","family":"Chaudhary","sequence":"additional","affiliation":[{"name":"Department of General Surgery, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naveen","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of General Surgery, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahaveer Singh","family":"Rodha","sequence":"additional","affiliation":[{"name":"Department of Trauma and Emergency, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahendra","family":"Lodha","sequence":"additional","affiliation":[{"name":"Department of General Surgery, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manoj Kumar","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Community Medicine and Family Medicine, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikhil","family":"Kothari","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Critical Care, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aditya","family":"Baksi","sequence":"additional","affiliation":[{"name":"Department of Surgical Disciplines, All India Institute of Medical Sciences, Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashok Kumar","family":"Puranik","sequence":"additional","affiliation":[{"name":"Executive Director, All India Institute of Medical Sciences, 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