{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:39:36Z","timestamp":1786653576696,"version":"build-2736575974"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,7]]},"abstract":"Abstract<\/jats:title>\n \n Introduction:<\/jats:title>\n Although laparoscopic cholecystectomy (LC) has become the gold standard for treating gall bladder stones (GBS), its safety in elderly patients is still questioned. This study aimed to assess the outcome of LC in patients 70 and older compared to younger patients.<\/jats:p>\n <\/jats:sec>\n \n Patients and Methods:<\/jats:title>\n The medical records of 548 patients undergoing LC were evaluated retrospectively. Patients\u2019 demographics and post-operative complications were recorded. Furthermore, patients were divided according to the CEPOD into emergency and elective patients, and complications were recorded according to Clavien\u2013Dindo (CD) classifications. Data analysis was performed with SPSS software version 27.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n Patients were divided into the elderly patients group (\u226570 years of age,\n n<\/jats:italic>\n = 185) and the young patients group (<70 years of age,\n n<\/jats:italic>\n = 363). The \u226570-year-old group showed a significantly higher number of patients who required emergency admission with GBS symptoms (\n P<\/jats:italic>\n = 0.001), emergency LC (\n P<\/jats:italic>\n = 0.01) and conversion to open (\n P<\/jats:italic>\n = 0.02). The two groups showed comparable post-operative complications: bile leak (\n P<\/jats:italic>\n = 0.26), collection (\n P<\/jats:italic>\n = 0.11) and re-operation (\n P<\/jats:italic>\n = 0.60), post-operative endoscopic retrograde cholangiopancreatography (\n P<\/jats:italic>\n = 1.0), GBS pancreatitis (\n P<\/jats:italic>\n = 0.33) and death (0.30). CD I\u2013II complications were higher in the \u2265 70-year-old group compared to the <70-year-old group in elective (\n P<\/jats:italic>\n = 0.01) and emergency (\n P<\/jats:italic>\n = 0.03) LC. However, CD \u22653 complications were higher in the \u226570-year-old group than the <70-year-old group in the emergency LC (\n P<\/jats:italic>\n = 0.01) and comparable in the elective LC (\n P<\/jats:italic>\n = 0.12).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n LC is safe and efficient in elderly patients. Elective LC should be expedited in elderly patients to avoid emergency admissions and emergency LC, which are associated with higher complication rates.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jmas.jmas_138_24","type":"journal-article","created":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T06:00:08Z","timestamp":1752472808000},"page":"265-269","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Laparoscopic cholecystectomy in elderly patients: Avoid or expedite? - A comparative cohort study"],"prefix":"10.4103","volume":"21","author":[{"given":"Maria","family":"Mondragon","sequence":"first","affiliation":[{"name":"Department of General Surgery, The Royal Wolverhampton NHS Trust, Wolverhampton, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali Yasen","family":"Mohamedahmed","sequence":"additional","affiliation":[{"name":"Department of General Surgery, The Royal Wolverhampton NHS Trust, Wolverhampton, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shafquat","family":"Zaman","sequence":"additional","affiliation":[{"name":"Department of General Surgery, The Dudley Group NHS Trust, Dudley, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ja\u2019quay","family":"Farquharson","sequence":"additional","affiliation":[{"name":"Department of General Surgery, The Royal Wolverhampton NHS Trust, Wolverhampton, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Usman","family":"Raja","sequence":"additional","affiliation":[{"name":"Department of General Surgery, The Royal Wolverhampton NHS Trust, Wolverhampton, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arhum","family":"Ijaz","sequence":"additional","affiliation":[{"name":"Department of General Surgery, The Royal Wolverhampton NHS Trust, Wolverhampton, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepak","family":"Singh-Ranger","sequence":"additional","affiliation":[{"name":"Department of General Surgery, The Royal Wolverhampton NHS Trust, Wolverhampton, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,7,14]]},"reference":[{"key":"R1-20250714","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1159\/000455241","article-title":"Early cholecystectomy for acute cholecystitis in the elderly population: A systematic review and meta-analysis","volume":"34","author":"Loozen","year":"2017","journal-title":"Dig Surg"},{"key":"R2-20250714","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1080\/00365520310008502","article-title":"Pain and quality of life in patients with symptomatic, non-complicated gallbladder stones: Results of a randomized controlled trial","volume":"39","author":"Vetrhus","year":"2004","journal-title":"Scand J Gastroenterol"},{"key":"R3-20250714","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1002\/bjs.9886","article-title":"Meta-analysis comparing early versus delayed laparoscopic cholecystectomy for acute cholecystitis","volume":"102","author":"Wu","year":"2015","journal-title":"Br J Surg"},{"key":"R4-20250714","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.ijsu.2015.04.083","article-title":"Open versus laparoscopic cholecystectomy in acute cholecystitis. 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