{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:48:48Z","timestamp":1787071728542,"version":"build-2736575974"},"reference-count":6,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Brunner\u2019s gland hyperplasia (also referred to as adenoma or hamartoma) is a rare, benign proliferative lesion of the duodenum. Although often asymptomatic, it can occasionally present with gastrointestinal (GI) bleeding, anaemia or obstructive symptoms. We report a case of a 65-year-old woman who presented with melena and symptomatic anaemia. Upper GI (UGI) endoscopy revealed multiple sessile polyps in the duodenum, with the largest measuring 2 cm. Given her history of a recent myocardial infarction and ongoing antiplatelet therapy, an endoscopic approach was chosen. Endoscopic mucosal resection (EMR) was successfully performed after temporarily withholding antiplatelets. Histopathology confirmed Brunner\u2019s gland hamartoma with no dysplasia or malignancy. The patient\u2019s haemoglobin levels improved, and follow-up endoscopy at 1 and 6 months showed no recurrence. Brunner\u2019s gland hyperplasia is a rare but important differential for upper GI bleeding. EMR or endoscopic snare polypectomy is a safe and effective treatment modality, particularly in high-risk surgical candidates.<\/jats:p>","DOI":"10.4103\/jmas.jmas_138_25","type":"journal-article","created":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T06:00:23Z","timestamp":1765000823000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["An unusual cause for Melena: The role of endoscopic mucosal resection in a rare case of the duodenal Brunner\u2019s gland hamartoma"],"prefix":"10.4103","author":[{"given":"Sundaram","family":"Easwaramoorthy","sequence":"first","affiliation":[{"name":"Department of Surgery, Lotus Hospital and Research Centre, Erode, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,12,5]]},"reference":[{"key":"R1-20260324","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1007\/s005950200179","article-title":"Giant Brunneroma as an unusual cause of upper gastrointestinal hemorrhage: Report of a case","volume":"32","author":"Tan","year":"2002","journal-title":"Surg Today"},{"key":"R2-20260324","first-page":"474","article-title":"Brunner's gland hyperplasia","volume":"55","author":"Peetz","year":"1989","journal-title":"Am Surg"},{"key":"R3-20260324","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1055\/s-2008-1069345","article-title":"Duodenal polyps. Incidence, histologic substrate and significance","volume":"109","author":"H\u00f6chter","year":"1984","journal-title":"Dtsch Med Wochenschr"},{"key":"R4-20260324","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1016\/S0016-5107(99)70408-6","article-title":"Characteristic EUS appearance of Brunner's gland hamartoma","volume":"49","author":"Matsushita","year":"1999","journal-title":"Gastrointest Endosc"},{"key":"R5-20260324","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/s005350200038","article-title":"Carcinoma of duodenum arising from Brunner's gland","volume":"37","author":"Akino","year":"2002","journal-title":"J Gastroenterol"},{"key":"R6-20260324","first-page":"348","article-title":"Brunner's gland hamartoma: \u2018Over-treatment\u2019 of a voluminous mass simulating a malignancy of the pancreatic-duodenal area","volume":"6","author":"Iusco","year":"2005","journal-title":"JOP"}],"container-title":["Journal of Minimal Access Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jmas.jmas_138_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:52:37Z","timestamp":1787068357000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jmas.jmas_138_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,5]]},"references-count":6,"URL":"https:\/\/doi.org\/10.4103\/jmas.jmas_138_25","relation":{},"ISSN":["0972-9941","1998-3921"],"issn-type":[{"value":"0972-9941","type":"print"},{"value":"1998-3921","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,5]]},"assertion":[{"value":"2025-04-08","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-22","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}