{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:40:38Z","timestamp":1786653638703,"version":"build-2736575974"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"Abstract<\/jats:title>\n \n Introduction:<\/jats:title>\n Shoulder tip pain (STP) is a post-operative complication seen in up to 60% of patients after LC. It occurs because of diaphragmatic irritation from residual carbon dioxide from pneumoperitoneum. This study evaluated the effect of intraperitoneal normal saline irrigation in relieving STP.<\/jats:p>\n <\/jats:sec>\n \n Patients and Methods:<\/jats:title>\n \n This randomised trial was conducted at Department of General Surgery, Government Medical College and Hospital, Chandigarh of North India between August 2024 and February 2025. A total of 158 patients underwent randomisation, and after exclusion, 63 participants were enrolled in Group A (intervention) and Group B (control). The Visual Analogue Scale (VAS) scores were measured at 6\n th<\/jats:sup>\n , 12\n th<\/jats:sup>\n , 24\n th<\/jats:sup>\n and 48\n th<\/jats:sup>\n h.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The mean age of the patients in Group A was 42.57 \u00b1 13.93 years and in Group B was 42.15 \u00b1 15.15 years (\n P<\/jats:italic>\n = 0.75). A female predominance was noted in both groups. The mean duration of surgery was slightly higher in Group A (36.19 \u00b1 11.82 min) compared to Group B (33.28 \u00b1 10.56 min) (\n P<\/jats:italic>\n = 0.860). The primary outcome was STP, evaluated using the VAS. At 6 h, mean VAS score was 1.31 in Group A versus 2.96 in Group B (\n P<\/jats:italic>\n = 0.000); at 12 h, 1.09 versus 2.84 (\n P<\/jats:italic>\n = 0.000); at 24 h, 0.53 versus 1.73 (\n P<\/jats:italic>\n = 0.0004) and at 48 h, 0.12 versus 0.76 (\n P<\/jats:italic>\n = 0.0006), highlighting the effectiveness of the intervention in reducing post-operative STP.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n This study demonstrates that intraperitoneal normal saline instillation is an effective and safe intervention for reducing STP after laparoscopic cholecystectomy.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jmas.jmas_171_25","type":"journal-article","created":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T12:00:06Z","timestamp":1759924806000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Effectiveness of intraperitoneal instillation of normal saline in reducing shoulder tip pain following laparoscopic cholecystectomy - A randomised controlled trial from North India"],"prefix":"10.4103","author":[{"given":"Anshul","family":"Kumar","sequence":"first","affiliation":[{"name":"Department of General Surgery, Government Medical College, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajesh Kumar","family":"Bansiwal","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Government Medical College, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agrawal Kavita","family":"Khemchand","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Government Medical College, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mandeep","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Government Medical College, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjeev","family":"Palta","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Government Medical College, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajeev","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Government Medical College, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,10,8]]},"reference":[{"key":"R1-20251008","doi-asserted-by":"crossref","first-page":"51","DOI":"10.22159\/ijcpr.2024v16i4.5008","article-title":"A comparative study between open cholecystectomy versus laparoscopic cholecystectomy","volume":"16","author":"Harsana","year":"2024","journal-title":"Int J Curr Pharm Res"},{"key":"R2-20251008","doi-asserted-by":"crossref","first-page":"2835","DOI":"10.21873\/invivo.13022","article-title":"Three-dimensional 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