{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T17:30:45Z","timestamp":1786728645803,"version":"build-2736575974"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p>Primary hyperparathyroidism secondary to ectopic parathyroid (in anterior mediastinum) is rare in children. We report the case of a 12-year-old girl with a history of multiple fractures, renal calculi and limb deformities. She was diagnosed with hyperparathyroidism secondary to an intrathymic parathyroid adenoma. Sestamibi scan showed a lesion in the anterior mediastinum. A biochemical evaluation revealed hypercalcaemia, elevated alkaline phosphatase and parathormone levels. The lesion was marked with radioisotope and confirmed intraoperatively using a gamma camera. The child underwent thoracoscopic left thymectomy with the adenoma. Immediate decrease in calcium and parathyroid hormone values were noted intraoperatively and serial monitoring showed a downward trend. On follow-up, the child is doing well. Ectopic parathyroid adenoma is very rare. CT with radioisotope scans is helpful in diagnosis. Thoracoscopic excision of ectopic adenoma is safe in children.<\/jats:p>","DOI":"10.4103\/jmas.jmas_190_22","type":"journal-article","created":{"date-parts":[[2023,3,18]],"date-time":"2023-03-18T07:39:17Z","timestamp":1679125157000},"page":"102-104","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Sestamibi-guided thoracoscopic excision of functional mediastinal parathyroid adenoma in a child: A case report and review of literature"],"prefix":"10.4103","volume":"20","author":[{"given":"Avilash","family":"Sahu","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery, Narayana Health, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. M.","family":"Zameer","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Narayana Health, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Narayana Health, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley","family":"D\u2019Cruz","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Narayana Health, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,3,14]]},"reference":[{"key":"R1-20240828","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1542\/peds.2004-0804","article-title":"Primary hyperparathyroidism in pediatric patients","volume":"115","author":"Kollars","year":"2005","journal-title":"Pediatrics"},{"key":"R2-20240828","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.ijscr.2019.03.014","article-title":"An anatomic aberration and a surgical challenge:Mediastinal parathyroid adenoma anterior the pericardium. A case report","volume":"57","author":"Patrinos","year":"2019","journal-title":"Int J Surg Case Rep"},{"key":"R3-20240828","doi-asserted-by":"crossref","first-page":"158","DOI":"10.3413\/nukmed-0108","article-title":"Preoperative localization of parathyroid lesions. Value of 99mTc-MIBI tomography and factors influencing detection","volume":"47","author":"Ansquer","year":"2008","journal-title":"Nuklearmedizin"},{"key":"R4-20240828","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1021\/acs.analchem.7b03617","article-title":"Raman spectroscopy applied to parathyroid tissues:A new diagnostic tool to discriminate normal tissue from adenoma","volume":"90","author":"Palermo","year":"2018","journal-title":"Anal Chem"},{"key":"R5-20240828","doi-asserted-by":"crossref","first-page":"14798","DOI":"10.1038\/s41598-017-14941-5","article-title":"Intraoperative assessment of parathyroid viability using laser speckle contrast imaging","volume":"7","author":"Mannoh","year":"2017","journal-title":"Sci Rep"},{"key":"R6-20240828","doi-asserted-by":"crossref","first-page":"3276","DOI":"10.1002\/hed.25837","article-title":"Efficacy of indocyanine green fluorescence in predicting parathyroid vascularization during thyroid surgery","volume":"41","author":"Razavi","year":"2019","journal-title":"Head Neck"},{"key":"R7-20240828","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1007\/s00268-011-1404-0","article-title":"Thoracoscopic removal of mediastinal parathyroid lesions:Selection of surgical approach and pitfalls of preoperative and intraoperative localization","volume":"36","author":"Iihara","year":"2012","journal-title":"World J Surg"},{"key":"R8-20240828","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1089\/lap.2007.0124","article-title":"Outpatient video-assisted thoracoscopic surgery (VATS) for ectopic mediastinal parathyroid adenoma:A case report and review of the literature","volume":"18","author":"Chae","year":"2008","journal-title":"J Laparoendosc Adv Surg Tech A"}],"container-title":["Journal of Minimal Access Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jmas.jmas_190_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T16:29:49Z","timestamp":1786724989000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jmas.jmas_190_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,14]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jmas.jmas_190_22","relation":{},"ISSN":["0972-9941","1998-3921"],"issn-type":[{"value":"0972-9941","type":"print"},{"value":"1998-3921","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,14]]},"assertion":[{"value":"2022-07-06","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-02","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}