{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:22:46Z","timestamp":1787840566661,"version":"build-2784847793"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Thyroid tumours are a common condition and open surgery is a conventional method for treating benign thyroid tumours when surgery is indicated. In this study, we evaluate the outcomes of benign thyroid tumour treatment using transoral endoscopic thyroidectomy via vestibular approach (TOETVA) and compare the results with those of conventional open thyroidectomy (COT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods:<\/jats:title>\n                    <jats:p>We conducted a prospective cohort study between 100 patients who underwent TOETVA and 100 who underwent COT surgery for benign diseases from June 2018 to December 2021 in our hospital. Outcomes between the two groups, including post-operative complications, operative time and length of stay, were compared.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The surgical time in the TOETVA group was significantly longer than in the COT group. The operative time of lobectomy in the TOETVA and COT groups was 77.5 \u00b1 13.3 and 51.5 \u00b1 4.2 min, respectively, with a\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001. The operative time of total thyroidectomy in the TOETVA and COT groups was 108.1 \u00b1 7.0 and 65.0 \u00b1 4.1 min, respectively, with a\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001. There was no difference in post-operative length of stay between the two groups. In TOETVA group, there were no patients who converted to open surgery. Amongst all 200 patients in the study, there were no cases of post-operative bleeding. The transient hypoparathyroidism rate after surgery in the TOETVA and COT groups was 3% and 2%, respectively, with no statistically significant difference (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.651). Similarly, the transient recurrent laryngeal nerve injury rate showed no difference between the two groups, with rates of 5% and 4% in the TOETVA and COT groups, respectively (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.733). There were no cases of post-operative infection in either group in our study. At 3 months postoperatively, the cosmetic satisfaction were significantly higher in the endoscopic groups than in the conventional group (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>TOETVA is a safe and effective method, with a low complication rate and optimal aesthetic results compared to traditional surgery to treat benign thyroid tumours.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jmas.jmas_197_23","type":"journal-article","created":{"date-parts":[[2024,1,12]],"date-time":"2024-01-12T08:00:37Z","timestamp":1705046437000},"page":"403-407","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Transoral endoscopic thyroidectomy vestibular approach versus conventional open thyroidectomy for the treatment of benign thyroid tumours: A prospective cohort study"],"prefix":"10.4103","volume":"20","author":[{"given":"Quy Xuan","family":"Ngo","sequence":"first","affiliation":[{"name":"Department of Head and Neck Surgery, Vietnam National Cancer Hospital, Thanh Tri District, Hanoi, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duy Quoc","family":"Ngo","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, Vietnam National Cancer Hospital, Thanh Tri District, Hanoi, Vietnam"},{"name":"Department of Oncology, Hanoi Medical University, Dong Da, Hanoi, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duong The","family":"Le","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, Vietnam National Cancer Hospital, Thanh Tri District, Hanoi, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duc Dinh","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, Vietnam National Cancer Hospital, Thanh Tri District, Hanoi, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toan Duc","family":"Tran","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, Vietnam National Cancer Hospital, Thanh Tri District, Hanoi, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quang Van","family":"Le","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, Vietnam National Cancer Hospital, Thanh Tri District, Hanoi, Vietnam"},{"name":"Department of Oncology, Hanoi Medical University, Dong Da, Hanoi, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,1,9]]},"reference":[{"key":"R1-20250109","doi-asserted-by":"crossref","first-page":"1764","DOI":"10.1056\/NEJMcp031436","article-title":"Clinical practice. 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