{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:32:24Z","timestamp":1787761944985,"version":"build-2784847793"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:p>\n                    Congenital chylous ascites (CCA) is a rare condition seen in the neonatal period. The pathogenesis is primarily related to congenital intestinal lymphangiectasis. Conservative treatment of chylous ascites involves paracentesis, total parenteral nutrition (TPN), medium-chain triglyceride (MCT)-based milk formula, use of somatostatin analogue and octreotide. Surgical treatment is considered when conservative treatment fails. We describe a laparoscopic treatment of CCA using the fibrin glue technique. A male infant, in whom foetal ascites was detected at 19 weeks of gestation, was born by caesarean section at 35 weeks of gestation weighing 3760 g. There was evidence of hydrops in the foetal scan. A diagnosis of chylous ascites was made by abdominal paracentesis. A magnetic resonance scan was suggestive of gross ascites, and no lymphatic malformation was identified. TPN and octreotide infusion was started and continued for 4 weeks, but the ascites persisted. The failure of conservative treatment led us to perform laparoscopic exploration. Intraoperatively, chylous ascites and multiple prominent lymphatic vessels around the root of the mesentery were noted. The fibrin glue was applied over the leaking mesenteric lymphatic vessels in the duodenopancreatic region. Oral feeding was started from post-operative day 7. After 2 weeks of the MCT formula, ascites progressed. Thus, laparoscopic exploration was necessary. We introduced an endoscopic applicator for fibrin glue and applied it into the place of leakage. The patient was doing well with no appearance of ascites reaccumulating and was discharged on the 45\n                    <jats:sup>th<\/jats:sup>\n                    post-operative day. Follow-up ultrasonography (1\n                    <jats:sup>st<\/jats:sup>\n                    , 3\n                    <jats:sup>rd<\/jats:sup>\n                    and 9\n                    <jats:sup>th<\/jats:sup>\n                    months after discharge) showed a small amount of ascitic fluid but with no clinical significance. Laparoscopic localisation and ligation of leakage sites could be difficult, especially in newborns and young infants due to the small size of lymphatic vessels. The use of fibrin glue to seal the lymphatic vessels is quite promising.\n                  <\/jats:p>","DOI":"10.4103\/jmas.jmas_304_22","type":"journal-article","created":{"date-parts":[[2023,5,15]],"date-time":"2023-05-15T05:00:29Z","timestamp":1684126829000},"page":"548-551","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Laparoscopic management of the congenital chylous ascites in a newborn: Case report"],"prefix":"10.4103","volume":"19","author":[{"given":"Petra","family":"Zahradnikova","sequence":"first","affiliation":[{"name":"Department of Paediatric Surgery, Faculty of Medicine, Comenius University in Bratislava, National Institute of Children\u2019s Diseases in Bratislava, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebeka","family":"Pechanova","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery, Faculty of Medicine, Comenius University in Bratislava, National Institute of Children\u2019s Diseases in Bratislava, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lenka","family":"Fedorova","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery, Faculty of Medicine, Comenius University in Bratislava, National Institute of Children\u2019s Diseases in Bratislava, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rene","family":"Jager","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery, Faculty of Medicine, Comenius University in Bratislava, National Institute of Children\u2019s Diseases in Bratislava, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbora","family":"Nedomova","sequence":"additional","affiliation":[{"name":"Department of Paediatric Anaesthesiology and Intensive Medicine, Faculty of Medicine, Comenius University in Bratislava, National Institute of Children\u2019s Diseases in Bratislava, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jozef","family":"Babala","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery, Faculty of Medicine, Comenius University in Bratislava, National Institute of Children\u2019s Diseases in Bratislava, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,5,10]]},"reference":[{"key":"R1-20240828","first-page":"175","article-title":"Diagnosis and management of congenital neonatal chylous ascites","volume":"16","author":"Mouravas","year":"2012","journal-title":"Hippokratia"},{"key":"R2-20240828","doi-asserted-by":"crossref","first-page":"bcr2012006196","DOI":"10.1136\/bcr-2012-006196","article-title":"Successful management of congenital chylous ascites with early octreotide and total parenteral nutrition in a newborn","author":"Olivieri","year":"2012","journal-title":"BMJ Case Rep 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