{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T13:19:08Z","timestamp":1787750348318,"version":"build-2784847793"},"reference-count":5,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Gastrointestinal polyps are associated with risks such as bleeding, intussusception, obstruction and malignancy, necessitating removal. Technological advancements in endoscopic and laparoscopic surgery have introduced minimally invasive options like laparoscopic intragastric surgery (LIGS), especially beneficial for polyps that cannot be resected endoscopically. This report presents a 37-year-old male patient with Peutz\u2013Jeghers Syndrome who exhibited symptoms of nausea, vomiting and weight loss. Endoscopy and computed tomography imaging revealed obstructive polyps in the bulbus and gastric cardia. The patient underwent single-port LIGS with preoperative botulinum toxin injection to facilitate pyloric opening. This combined approach allowed effective lesion resection without requiring extensive gastric resection. Pathology confirmed a hamartomatous polyp in the bulbus and high-grade dysplasia with negative margin in the gastric cardia. LIGS, particularly with botulinum toxin assistance, appears to be a safe and effective method for excising intraluminal lesions in complex anatomical areas, such as the duodenal bulbus and cardia.<\/jats:p>","DOI":"10.4103\/jmas.jmas_352_24","type":"journal-article","created":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T23:01:12Z","timestamp":1782428472000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Pyloric botulinum toxin injection and single-port laparoscopic intragastric surgery for bulbus hamartoma"],"prefix":"10.4103","author":[{"given":"Deniz","family":"Tikici","sequence":"first","affiliation":[{"name":"Department of Gastroenterological Surgery, Gazi Yasargil Training and Research Hospital, Diyarbakir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salim Ilksen","family":"Basceken","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology, Gazi Yasargil Training and Research Hospital, Diyarbakir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,6,25]]},"reference":[{"key":"R1-20260629","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.jviscsurg.2020.10.017","article-title":"Results of laparoscopic intragastric surgery","volume":"158","author":"Bonnet","year":"2021","journal-title":"J Visc Surg"},{"key":"R2-20260629","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/164_2019_326","article-title":"Gastrointestinal uses of botulinum toxin","volume":"263","author":"Cariati","year":"2021","journal-title":"Handb Exp Pharmacol"},{"key":"R3-20260629","doi-asserted-by":"crossref","first-page":"193","DOI":"10.5152\/tjg.2024.24080","article-title":"Long-term efficacy of single-\u0131ncision laparoscopic \u0131ntragastric resection in treating gastrointestinal stromal tumors","volume":"35","author":"Umman","year":"2024","journal-title":"Turk J Gastroenterol"},{"key":"R4-20260629","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1089\/lap.2021.0186","article-title":"Single-\u0131ncision laparoscopic \u0131ntragastric surgery for gastric submucosal tumors located near the esophagogastric junction","volume":"32","author":"Zhang","year":"2022","journal-title":"J Laparoendosc Adv Surg Tech A"},{"key":"R5-20260629","doi-asserted-by":"crossref","first-page":"2484","DOI":"10.1016\/j.asjsur.2024.01.095","article-title":"Three-\u0131ncision laparoscopic intragastric surgery for gastric submucosal tumors located near the esophagogastric junction: A technical note","volume":"47","author":"Zeng","year":"2024","journal-title":"Asian J Surg"}],"container-title":["Journal of Minimal Access Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jmas.jmas_352_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T12:26:28Z","timestamp":1787747188000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jmas.jmas_352_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,25]]},"references-count":5,"URL":"https:\/\/doi.org\/10.4103\/jmas.jmas_352_24","relation":{},"ISSN":["0972-9941","1998-3921"],"issn-type":[{"value":"0972-9941","type":"print"},{"value":"1998-3921","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,25]]},"assertion":[{"value":"2024-11-25","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-31","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}