{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:30:44Z","timestamp":1786649444251,"version":"build-2736575974"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"Abstract<\/jats:title>\n \n Introduction:<\/jats:title>\n Malignant pleural effusion (MPE) is a common complication of advanced cancer that impairs quality of life. The present study compared the outcomes of three procedures: tube thoracostomy with talc pleurodesis, video-assisted thoracoscopic surgery (VATS) with talc and indwelling pleural catheter (IPC).<\/jats:p>\n <\/jats:sec>\n \n Patients and Methods:<\/jats:title>\n \n In this retrospective study, 76 MPE patients were assigned to tube + talc (\n n<\/jats:italic>\n = 29), VATS + talc (\n n<\/jats:italic>\n = 27) or IPC (\n n<\/jats:italic>\n = 20). Outcomes included pleurodesis success, complications, hospitalisation, 30-day reintervention, mortality and overall survival. Eastern Cooperative Oncology Group (ECOG) performance score and serum albumin were analysed as prognostic factors using Cox regression.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n IPC had the shortest hospital stay (3 days) and the highest 30-day reintervention rate (20%,\n P<\/jats:italic>\n = 0.030). Pleurodesis success was 84.6% in both the tube and VATS groups. Median survival differed among groups (66 days for IPC, 95 days for tube and 118 days for VATS;\n P<\/jats:italic>\n = 0.041); however, procedure type was not an independent predictor of survival, and these differences should be interpreted cautiously. ECOG \u22652 (hazard ratio [HR]: 1.74,\n P<\/jats:italic>\n = 0.020) and albumin <3.0 g\/dL (HR: 1.60,\n P<\/jats:italic>\n = 0.040) were identified as independent predictors of poorer survival.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Treatment selection should primarily be based on functional and nutritional status rather than expected survival benefit. ECOG performance status and serum albumin levels should play a central role in guiding individualised management strategies.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jmas.jmas_487_25","type":"journal-article","created":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T08:02:49Z","timestamp":1776067369000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Clinical outcomes of video-assisted thoracoscopic surgery, talc pleurodesis and indwelling catheterisation for malignant pleural effusion: A retrospective comparative study"],"prefix":"10.4103","author":[{"given":"Turkan","family":"Dubus","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, Hamidiye Faculty of Medicine, Basaksehir Cam and Sakura City Hospital, University of Health Sciences, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erman Bagatur","family":"Ozturk","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Kanuni Training and Research Hospital, University of Health Sciences, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gokce","family":"Cangel","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Sultangazi Haseki Training and Research Hospital, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ozlem","family":"Ceyran","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine, Istanbul Training and Research Hospital, University of Health Sciences, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,4,13]]},"reference":[{"key":"R1-20260413","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1136\/thorax-2023-220304","article-title":"British Thoracic Society Guideline for pleural 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