{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:31:30Z","timestamp":1787761890326,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Cholelithiasis is uncommon in childhood but is more likely to present with symptoms that adversely affect the quality of life (QoL). This study assessed patient-reported outcomes after laparoscopic cholecystectomy (LC) using a paediatric-specific gastrointestinal (GI) health-related quality-of-life tool at a tertiary care centre in northern India.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods:<\/jats:title>\n                    <jats:p>A retrospective study of a cohort of children aged &lt;12 years who underwent LC between 2016 and 2022 was performed. The PedsQL\u2122 GI module questionnaire was administered to the patients or their parents, and the change in the QoL after surgery was evaluated across 14 GI symptom-related domains.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Thirty-five children (23 males: 12 females) with a mean age of 7.24 years (standard deviation [SD]: 3.27) were recruited. The most common indication for surgery was biliary colic (70.3%). The mean post-operative hospital stay was 1.7 days. At a mean follow-up of 52.6 months (SD: 29.7), there was a significant improvement in the mean PedsQL\u2122 GI score after surgery (93.37 [\u00b15.2] vs. 99.65 [\u00b11.35],\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.0001). The domains of stomach pain, stomach discomfort, nausea and vomiting and worry about stomach aches showed significant improvement after LC.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>LC for paediatric cholelithiasis results in a significant improvement in QoL following surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jmas.jmas_583_25","type":"journal-article","created":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T14:00:15Z","timestamp":1780927215000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Laparoscopic cholecystectomy in the paediatric population: A quality-of-life study"],"prefix":"10.4103","author":[{"given":"Palak","family":"Singhai","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muneer Abas","family":"Malik","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nitin James","family":"Peters","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jai Kumar","family":"Mahajan","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,6,5]]},"reference":[{"key":"R1-20260608","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1007\/s13312-010-0159-2","article-title":"Gallstone disease in children","volume":"47","author":"Poddar","year":"2010","journal-title":"Indian Pediatr"},{"key":"R2-20260608","doi-asserted-by":"crossref","first-page":"246","DOI":"10.18203\/2349-2902.isj20164450","article-title":"Evaluation and management of cholelithiasis in children: A hospital based study","volume":"4","author":"Bhasin","year":"2016","journal-title":"Int Surg J"},{"key":"R4-20260608","doi-asserted-by":"crossref","first-page":"93","DOI":"10.4103\/0972-9941.59306","article-title":"Pediatric cholelithiasis and laparoscopic management: A review of twenty two cases","volume":"5","author":"Deepak","year":"2009","journal-title":"J Minim Access Surg"},{"key":"R5-20260608","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.amjsurg.2006.01.020","article-title":"Improvement in gastrointestinal symptoms and quality of life after cholecystectomy","volume":"192","author":"Finan","year":"2006","journal-title":"Am J Surg"},{"key":"R6-20260608","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1007\/s00464-003-9263-x","article-title":"Evaluation of quality of life after laparoscopic surgery: Evidence-based guidelines of the European Association for Endoscopic Surgery","volume":"18","author":"Korolija","year":"2004","journal-title":"Surg Endosc"},{"key":"R7-20260608","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1007\/s11605-008-0526-7","article-title":"Responsiveness and minimal clinically important differences after cholecystectomy: GIQLI versus SF-36","volume":"12","author":"Shi","year":"2008","journal-title":"J Gastrointest Surg"},{"key":"R8-20260608","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1097\/MPG.0000000000000414","article-title":"PedsQL gastrointestinal symptoms module: Feasibility, reliability, and validity","volume":"59","author":"Varni","year":"2014","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"R9-20260608","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1089\/lap.2010.0425","article-title":"Bile duct injuries during pediatric laparoscopic cholecystectomy: A national perspective","volume":"21","author":"Raval","year":"2011","journal-title":"J Laparoendosc Adv Surg Tech A"},{"key":"R10-20260608","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1007\/s00464-001-9015-8","article-title":"Gastrointestinal quality of life in patients with symptomatic or asymptomatic cholelithiasis before and after laparoscopic cholecystectomy","volume":"15","author":"Mentes","year":"2001","journal-title":"Surg Endosc"},{"key":"R11-20260608","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1007\/s00464-001-9231-2","article-title":"Comparison of long-term quality of life after laparoscopic and open cholecystectomy","volume":"17","author":"Top\u00e7u","year":"2003","journal-title":"Surg Endosc"}],"container-title":["Journal of Minimal Access Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jmas.jmas_583_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:07:22Z","timestamp":1787760442000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jmas.jmas_583_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,5]]},"references-count":10,"URL":"https:\/\/doi.org\/10.4103\/jmas.jmas_583_25","relation":{},"ISSN":["0972-9941","1998-3921"],"issn-type":[{"value":"0972-9941","type":"print"},{"value":"1998-3921","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,5]]},"assertion":[{"value":"2025-12-29","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-08","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}