{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:32:18Z","timestamp":1787758338315,"version":"build-2784847793"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background and Objectives:<\/jats:title>\n                    <jats:p>Salivary gland tumors (SGTs) are serious challenges to pathologists. Herein, we aimed to assess epidemiological and histopathological characteristics of SGTs among Sudanese patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>This retrospective descriptive study was undertaken at The pathology department in Khartoum State between 2008 and 2018. Patient records, histopathological reports, and slides were retrieved; and re-examined by two histopathologists. Diagnoses were reclassified according to the 2017 WHO classification of SGTs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Overall, 150 cases of Sudanese patients with SGT were included (90 [60%] males and 60 [40%] females). Among these, 105 were benign (70%) and 45 were malignant (30%). The parotid glands were the most common site for both benign and malignant tumors (77\/150; 51%: 59 benign (76.6%) and 18 malignant [23.4%]). The next common site was the submandibular gland (54 [36%]: 38 benign [70.3%] and 16 malignant [29.7%]), followed by minor salivary glands (19 [12.7%]: 8 benign and 11 malignant [57.9%]). Benign gland entities included pleomorphic adenoma (88\/105; 83.7%), oncocytoma (5\/105; 4.8%), myoepithelioma (4\/105; 3.8%), Whartin tumors (3\/105; 2.9%), basal cell adenoma (3\/105; 2.9%), and sialolipoma (2\/105; 1.9%). Malignant gland entities included adenoid cystic carcinoma (12; 26.7%), mucoepidermoid carcinoma (10; 22,2%), acinic cell carcinoma (6; 13.3%), poorly differentiated carcinoma (4; 8.9%), adenocarcinoma NOS (not otherwise specified) (4; 8.9%), basal cell adenocarcinoma (3; 6.7%), carcinoma ex pleomorphic adenoma (3; 6.7%), polymorphous adenocarcinoma (2; 4.4%), salivary duct carcinoma (1; 2.2%), and epithelial\u2013myoepithelial carcinoma (2.2%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>SGTs shared several epidemiological and histopathological features, exhibiting high incidence in the parotid and submandibular glands, lower prevalence in minor glands, and greater male predominance.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jmau.jmau_113_20","type":"journal-article","created":{"date-parts":[[2022,11,8]],"date-time":"2022-11-08T04:47:32Z","timestamp":1667882852000},"page":"92-96","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Epidemiological, Clinical, and Histopathological Features of Salivary Gland Tumors among 150 Sudanese Patients: 10 Years\u2019 Experience"],"prefix":"10.4103","volume":"11","author":[{"given":"Somaya T. S.","family":"Hamid","sequence":"first","affiliation":[{"name":"Department of Pathology, Faculty of Medicine, Omdurman Islamic University, Khartoum, Sudan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed A. M.","family":"Abdalla","sequence":"additional","affiliation":[{"name":"Department of Peadiatrics, Faculty of Medicine, Khartoum University, Khartoum, Sudan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azza A.","family":"Zulfu","sequence":"additional","affiliation":[{"name":"Department of Pathology, Faculty of Medicine, Omdurman Islamic University, Khartoum, Sudan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azza","family":"Ramadan","sequence":"additional","affiliation":[{"name":"College of Pharmacy, Al Ain University, Abu Dhabi Campus-Abu Dhbai, United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Musaab","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Basic Medical Sciences, College of Medicine, Ajman University, Ajman, United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed H.","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Medicine, HIV Metabolic Clinic, Milton Keynes University Hospital NHS Foundation Trust, Eagelstone, Milton Keynes, Buckinghamshire, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,11,9]]},"reference":[{"key":"R1-20240830","first-page":"Doc12","article-title":"Current aspects of salivary gland tumors \u2013A systematic review of the literature","volume":"8","author":"Galdirs","year":"2019","journal-title":"GMS Interdiscip Plast Reconstr Surg DGPW"},{"key":"R2-20240830","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.otot.2018.06.001","article-title":"Pathology of benign and malignant neoplasms of salivary glands","volume":"29","author":"Lubin","year":"2018","journal-title":"Oper Tech Otolaryngol Head Neck Surg"},{"key":"R3-20240830","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.mpdhp.2020.01.001","article-title":"Salivary gland tumours:Diagnostic challenges and an update on the latest WHO classification","volume":"26","author":"Speight","year":"2020","journal-title":"Diagn Histopathol"},{"key":"R4-20240830","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.scitotenv.2010.09.010","article-title":"Cancer in the Sudan:An overview of the current status of knowledge on tumor patterns and risk factors","volume":"423","author":"Awadelkarim","year":"2012","journal-title":"Sci Total Environ"},{"issue":"6","key":"R5-20240830","first-page":"1645","article-title":"Oral Cancer Awareness in Sudan:Assessment of Knowledge, Attitude and Treatment Seeking Behavior","volume":"18","author":"Eltayeb","journal-title":"Asian Pac J Cancer Prev. 2017 Jun 25"},{"key":"R6-20240830","first-page":"214","article-title":"Salivary gland tumours in the Sudan","volume":"70","author":"Fahal","year":"1993","journal-title":"East Afr Med J"},{"key":"R7-20240830","first-page":"29","article-title":"The incidence of salivary glands tumors among the Sudanese","volume":"2","author":"Suleiman","year":"2003","journal-title":"Pakistan Journal of Orthodontics, Pediatric and Community Dentistry"},{"key":"R8-20240830","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1002\/ijc.2910610202","article-title":"Descriptive epidemiology of oral neoplasms in Sudan 1970-1985 and the role of toombak","volume":"61","author":"Idris","year":"1995","journal-title":"Int J Cancer"},{"key":"R9-20240830","first-page":"105","article-title":"Pattern of head and neck malignancies in Central Sudan-(study of 314 cases)","volume":"3","author":"Abuidris","year":"2008","journal-title":"Sudan J Med Sci"},{"key":"R10-20240830","first-page":"52","article-title":"Histopathological patterns of oral lesions among Sudanese patients","volume":"1","author":"Badie","year":"2015","journal-title":"Clin Med"},{"key":"R11-20240830","first-page":"26","article-title":"Frequency of oral cancers among cancers in Sudanese patients (2009\u20132016)","volume":"5","author":"Salah","year":"2017","journal-title":"Adv Med Dent Sci Res"},{"key":"R12-20240830","first-page":"5","article-title":"Tumours of salivary glands in Sudan","volume":"5","author":"Ahmed","year":"2018","journal-title":"Int J Orl"},{"key":"R13-20240830","first-page":"15","article-title":"Salivary gland tumors in Uganda:Clinical pathological study","volume":"4","author":"Vuhahula","year":"2004","journal-title":"Afr Health Sci"},{"key":"R14-20240830","doi-asserted-by":"crossref","first-page":"e53","DOI":"10.1016\/j.tripleo.2006.11.017","article-title":"Salivary tumors in north Jordanians:A descriptive study","volume":"103","author":"Al-Khateeb","year":"2007","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"R15-20240830","doi-asserted-by":"crossref","first-page":"2187","DOI":"10.1016\/j.joms.2006.11.025","article-title":"Salivary gland tumors in an Iranian population:A retrospective study of 130 cases","volume":"65","author":"Ansari","year":"2007","journal-title":"J Oral Maxillofac Surg"},{"key":"R16-20240830","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.bjoms.2008.03.020","article-title":"Salivary gland tumors:A single institution experience in India","volume":"46","author":"Subhashraj","year":"2008","journal-title":"Br J Oral Maxillofac Surg"},{"key":"R17-20240830","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.ijom.2005.02.005","article-title":"Salivary gland tumors in a Brazilian population:A retrospective study of 496 cases","volume":"34","author":"Ito","year":"2005","journal-title":"Int J Oral Maxillofac Surg"}],"container-title":["Journal of Microscopy and Ultrastructure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jmau.jmau_113_20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:14:25Z","timestamp":1787757265000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jmau.jmau_113_20"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,9]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/jmau.jmau_113_20","relation":{},"ISSN":["2213-879X","2213-8803"],"issn-type":[{"value":"2213-879X","type":"print"},{"value":"2213-8803","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,9]]},"assertion":[{"value":"2020-11-01","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-18","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}