{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T20:28:10Z","timestamp":1786739290850,"version":"build-2736575974"},"reference-count":58,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      For many decades, scientists were unable to expose the invisible existence of the parasites in their living hosts, except by scarification and then dissection of the animal model. This process just demonstrates a dead parasite in a dead host. Using this approach, very limited information can be obtained concerning the dynamics of infection and the pathways utilized by the parasite to survive within a hostile host's environment. Introduction of ultra-high-speed imaging techniques, with a time domain of barely few microseconds or even less, has revolutionized the \u201c\n                      <jats:italic toggle=\"yes\">in vivo<\/jats:italic>\n                      dissection\u201d of the parasites. Such methods provide platforms for imaging host\u2013parasite interactions at diverse scales, down to the molecular level. These have complementary advantages and relative assets in investigating host\u2013parasite interactions. Therefore, better elucidation of such interaction may require the usage of more than one approach. Precise\n                      <jats:italic toggle=\"yes\">in vivo<\/jats:italic>\n                      quantification, of the parasite load within the host, and better insight into the kinetics of infection are the two main advantages of the novel imaging procedures. However, imaging parasite\u2013host interplay is still a challenging approach due to many constraints related to the parasite biology, the tissue environment within which the parasites exist, and the logistic technical limitations. This review was planned to assist better understanding of how much the new imaging techniques impacted the recent advances in parasite biology, especially the immunobiology of protozoan parasites.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jmau.jmau_1_20","type":"journal-article","created":{"date-parts":[[2020,5,8]],"date-time":"2020-05-08T05:10:58Z","timestamp":1588914658000},"page":"1-6","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["The Parasites Caught In-Action"],"prefix":"10.4103","volume":"9","author":[{"given":"Mohammed A.","family":"Afifi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-1-20240830","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.exppara.2010.05.014","article-title":"Imaging of the host\/parasite interplay in cutaneous 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