{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T09:15:48Z","timestamp":1793438148640,"version":"4.5.0"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>RosaiDorfman disease (RDD) is a rare, self-limiting disease of uncertain etiology involving lymph nodes as well as extranodal sites. Isolated or pure cutaneous RDD (PCRDD) without lymph node involvement is very unusual accounting for only 3% of all described cases of RDD. The clinical features of PCRDD are quite different from RDD according to the literature on extranodal RDD, thereby emphasizing that PCRDD is a distinct clinical entity. Histopathology remains the gold standard for the diagnosis of both systemic and PCRDD with the presence of characteristic emperipolesis observed in histiocytes while immunohistochemistry (IHC) (S100, CD 68 positive, and CD 1a-negative) serves as a useful adjunct. We hereby report a case of a 36-year-old female who presented with a tender, indurated plaque on the left forearm with a clinical differential diagnosis of borderline tuberculoid leprosy\/sarcoidosis and lupus vulgaris. However, on histopathology, a diagnosis of RDD was performed and confirmed on IHC. This case highlights the need to create awareness among young pathologists and clinicians about PCRDD to prevent overzealous treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jmau.jmau_76_20","type":"journal-article","created":{"date-parts":[[2021,9,7]],"date-time":"2021-09-07T09:22:09Z","timestamp":1631006529000},"page":"90-92","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Pure Cutaneous Rosai Dorfman Disease"],"prefix":"10.4103","volume":"10","author":[{"given":"Manjula","family":"Jain","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mukta","family":"Pujani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dipti","family":"Sidam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruchira","family":"Wadhwa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanta","family":"Passi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepika","family":"Uikey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-9-20240830","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1097\/00000372-200210000-00001","article-title":"Cutaneous rosai-dorfman disease is a distinct clinical entity","volume":"24","author":"Brenn","year":"2002","journal-title":"Am J Dermatopathol"},{"key":"R2-9-20240830","first-page":"63","article-title":"Sinus histiocytosis with massive lymphadenopathy. A newly recognized benign clinicopathological entity","volume":"87","author":"Rosai","year":"1969","journal-title":"Arch Pathol"},{"key":"R3-9-20240830","first-page":"19","article-title":"Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease): Review of the entity","volume":"7","author":"Foucar","year":"1990","journal-title":"Semin Diagn Pathol"},{"key":"R4-9-20240830","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1093\/ajcp\/aqv029","article-title":"Extranodal rosai-dorfman disease: Clinicopathologic series of 10 patients with radiologic correlation and review of the literature","volume":"145","author":"Mantilla","year":"2016","journal-title":"Am J Clin Pathol"},{"key":"R5-9-20240830","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1097\/01.pas.0000213387.70783.b6","article-title":"Cutaneous rosai-dorfman disease: A clinical and histopathologic study of 25 cases in China","volume":"31","author":"Kong","year":"2007","journal-title":"Am J Surg Pathol"},{"key":"R6-9-20240830","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1111\/j.1365-2133.2005.06917.x","article-title":"Cutaneous Rosai-Dorfman disease: Clinicopathological profiles, spectrum and evolution of 21 lesions in six patients","volume":"154","author":"Wang","year":"2006","journal-title":"Br J Dermatol"},{"key":"R7-9-20240830","doi-asserted-by":"crossref","first-page":"447","DOI":"10.4103\/0019-5154.119953","article-title":"Purely cutaneous rosai-dorfman disease with immunohistochemistry","volume":"58","author":"Farooq","year":"2013","journal-title":"Indian J Dermatol"},{"key":"R8-9-20240830","doi-asserted-by":"crossref","first-page":"60","DOI":"10.4103\/0377-4929.116154","article-title":"Cutaneous Rosai-Dorfman disease: Report of a case","volume":"56","author":"Singh","year":"2013","journal-title":"Indian J Pathol Microbiol"},{"key":"R9-9-20240830","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.jdds.2017.06.005","article-title":"Cutaneous Rosai-Dorfman disease: A separate clinical entity","volume":"21","author":"Hinojosa","year":"2017","journal-title":"J Dermatol Dermatol Surg"}],"container-title":["Journal of Microscopy and Ultrastructure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/JMAU.JMAU_76_20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T19:33:47Z","timestamp":1786736027000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/JMAU.JMAU_76_20"}},"subtitle":["An Uncommon Location for a Rare Histiocytic Proliferative Disorder"],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":9,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/jmau.jmau_76_20","relation":{},"ISSN":["2213-879X"],"issn-type":[{"value":"2213-879X","type":"print"}],"subject":[],"published":{"date-parts":[[2022,4]]}}}