{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:32:21Z","timestamp":1787776341926,"version":"build-2784847793"},"reference-count":31,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,1]]},"abstract":"\n A\n BSTRACT<\/jats:sc>\n <\/jats:title>\n \n Background:<\/jats:title>\n Sarcopenia, characterized by loss of muscle mass and function, is a significant health concern in aging populations. While its physical consequences are well-documented, the relationship between sarcopenia and mental health remains understudied. This study aimed to investigate the prevalence of sarcopenia and its association with mental health status, including depression, cognitive function, anxiety, and loneliness, among elderly patients.<\/jats:p>\n <\/jats:sec>\n \n Methodology:<\/jats:title>\n A comparative cross-sectional study was conducted on 407 participants aged \u226565. Sarcopenia was diagnosed using the modified Asian Working Group for Sarcopenia criteria. Mental health was assessed using validated scales: the 15-item Geriatric Depression Scale, the Mini-Mental State Examination, the 7-item Generalized Anxiety Disorder Scale, and the 3-item UCLA Loneliness Scale (UCLA-3). Logistic regression models were used to examine associations between sarcopenia and mental health outcomes.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The prevalence of sarcopenia was 49.9% (95% confidence interval [CI]: 45.0%\u201354.8%), with higher rates in older age groups and women. After adjusting for confounders, sarcopenia was significantly associated with depression (odds ratio [OR]: 2.28, 95% CI: 1.51\u20133.44,\n P<\/jats:italic>\n < 0.001) and cognitive impairment (OR: 1.86, 95% CI: 1.17\u20132.96,\n P<\/jats:italic>\n = 0.009). Associations with anxiety (OR: 1.49, 95% CI: 0.93\u20132.38,\n P<\/jats:italic>\n = 0.095) and loneliness (OR: 1.52, 95% CI: 1.00\u20132.31,\n P<\/jats:italic>\n = 0.049) were observed but did not reach statistical significance.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Sarcopenia is highly prevalent among elderly patients and is independently associated with adverse mental health outcomes, particularly depression and cognitive impairment. These findings underscore the importance of integrated physical and mental health interventions in the care of older adults with sarcopenia.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jmh.jmh_154_24","type":"journal-article","created":{"date-parts":[[2025,4,7]],"date-time":"2025-04-07T16:19:12Z","timestamp":1744042752000},"page":"51-59","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Prevalence of Sarcopenia and Its Association with Mental Health Status in Elderly Patients: A Comparative Cross-sectional Study"],"prefix":"10.4103","volume":"16","author":[{"given":"M","family":"Yogesh","sequence":"first","affiliation":[{"name":"Department of Community Medicine, Shri MP Shah Medical College, Jamnagar, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anjali","family":"Dave","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Shri MP Shah Medical College, Jamnagar, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jimmy","family":"Kagathara","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Smt B K Shah Medical Institute and Research Centre, Sumandeep Vidyapeeth Deemed to be University, Piparia, Vadodara, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohankumar","family":"Gandhi","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Shri MP Shah Medical College, Jamnagar, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhruv","family":"Lakkad","sequence":"additional","affiliation":[{"name":"Medical Student, Shri MP Shah Medical College, Jamnagar, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,4,7]]},"reference":[{"key":"R2-20250415","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1093\/ageing\/afy169","article-title":"Sarcopenia: Revised European consensus on definition and diagnosis","volume":"48","author":"Cruz-Jentoft","year":"2019","journal-title":"Age Ageing"},{"key":"R3-20250415","doi-asserted-by":"crossref","first-page":"e0169548","DOI":"10.1371\/journal.pone.0169548","article-title":"Health outcomes of sarcopenia: A systematic review and meta-analysis","volume":"12","author":"Beaudart","year":"2017","journal-title":"PLoS One"},{"key":"R4-20250415","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s40200-017-0302-x","article-title":"Prevalence of sarcopenia in the world: A systematic review and meta- analysis of general population studies","volume":"16","author":"Shafiee","year":"2017","journal-title":"J Diabetes Metab Disord"},{"key":"R5-20250415","doi-asserted-by":"crossref","first-page":"1263553","DOI":"10.3389\/fpsyt.2023.1263553","article-title":"Depression and risk of sarcopenia: A national cohort and Mendelian randomization study","volume":"14","author":"Zhong","year":"2023","journal-title":"Front Psychiatry"},{"key":"R6-20250415","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.socscimed.2017.11.008","article-title":"The relationship between physical and mental health: A mediation analysis","volume":"195","author":"Ohrnberger","year":"2017","journal-title":"Soc Sci Med"},{"key":"R7-20250415","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1186\/1741-7015-11-129","article-title":"Understanding the somatic consequences of depression: Biological mechanisms and the role of depression symptom profile","volume":"11","author":"Penninx","year":"2013","journal-title":"BMC Med"},{"key":"R8-20250415","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1038\/ijo.2015.124","article-title":"Sarcopenic obesity and risk of new onset depressive symptoms in older adults: English longitudinal study of ageing","volume":"39","author":"Hamer","year":"2015","journal-title":"Int J Obes (Lond)"},{"key":"R9-20250415","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1007\/s12603-019-1188-8","article-title":"Sarcopenia is associated with cognitive impairment in older adults: A systematic review and meta-analysis","volume":"23","author":"Cabett","year":"2019","journal-title":"J Nutr Health Aging"},{"key":"R10-20250415","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1007\/s12603-016-0843-6","article-title":"Prospective associations of low muscle mass and function with 10-year falls risk, incident fracture and mortality in community-dwelling older adults","volume":"21","author":"Balogun","year":"2017","journal-title":"J Nutr Health Aging"},{"key":"R11-20250415","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","article-title":"Mini-mental state. 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