{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T00:19:20Z","timestamp":1793924360771,"version":"4.8.0"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:sec>\n                    <jats:title>Aims and Objectives:<\/jats:title>\n                    <jats:p>The aim of this study was to determine the diagnostic accuracy of a hysteroscopic scoring system in predicting endometrial cancer and endometrial hyperplasia with atypia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>This is a prospective study involving 95 peri and postmenopausal women with abnormal uterine bleeding who underwent hysteroscopic-guided endometrial biopsy. After the calculation of hysteroscopic score, biopsy was obtained and sent for histopathological examination. Hysteroscopic diagnosis of carcinoma endometrium was made when the total score was \u226516 and a score \u22657 supported a diagnosis of endometrial hyperplasia with atypia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Out of the 95 women, 46 (48.4%) women had postmenopausal bleeding. The mean age of women was 50.4 \u00b1 10.3 years. Eight women were diagnosed to have endometrial cancer and eight had endometrial hyperplasia with atypia on histopathological examination. Using a hysteroscopy score \u226516, the sensitivity and specificity were found to be 62.5% and 90.8%, respectively, for diagnosing endometrial cancer. Hysteroscopy score \u22659 was found to be a better cutoff for diagnosing endometrial cancer using Youden index. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) for diagnosing endometrial cancer with score \u22659 was 100%, 67.8%, 22.2%, and 100%, respectively. The sensitivity, specificity, PPV, and NPV for diagnosing endometrial hyperplasia with atypia with score \u22657 was found to be 75%, 58.6%, 14.3%, and 96.2%, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The hysteroscopic scoring system has a good diagnostic performance when a cutoff score \u22659 is used in predicting endometrial cancer. However, the scoring system has lower diagnostic accuracy in predicting endometrial hyperplasia with atypia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jmh.jmh_246_20","type":"journal-article","created":{"date-parts":[[2021,11,3]],"date-time":"2021-11-03T02:57:50Z","timestamp":1635908270000},"page":"206-210","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":6,"title":["Diagnostic Accuracy of Hysteroscopic Scoring System in Predicting Endometrial Malignancy and Atypical Endometrial Hyperplasia"],"prefix":"10.4103","volume":"12","author":[{"given":"Bhukya","family":"Harika","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology, JIPMER, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murali","family":"Subbaiah","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, JIPMER, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilip Kumar","family":"Maurya","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, JIPMER, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2021,10,16]]},"reference":[{"key":"R1-20250529","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1093\/jnci\/djx214","article-title":"International patterns and trends in endometrial cancer incidence, 1978-2013","volume":"110","author":"Lortet-Tieulent","year":"2018","journal-title":"J Natl Cancer Inst"},{"key":"R2-20250529","doi-asserted-by":"crossref","first-page":"309","DOI":"10.2174\/1574887110666150923115228","article-title":"Management of endometrial cancer: A review","volume":"10","author":"Suri","year":"2015","journal-title":"Rev Recent Clin Trials"},{"key":"R3-20250529","doi-asserted-by":"crossref","first-page":"e138","DOI":"10.1097\/AOG.0000000000003712","article-title":"The use of hysteroscopy for the diagnosis and treatment of intrauterine pathology: ACOG committee opinion, number 800","volume":"135","year":"2020","journal-title":"Obstet Gynecol"},{"key":"R4-20250529","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1034\/j.1600-0412.2001.801210.x","article-title":"Dilatation and curettage fails to detect most focal lesions in the uterine cavity in women with postmenopausal bleeding","volume":"80","author":"Epstein","year":"2001","journal-title":"Acta Obstet Gynecol Scand"},{"key":"R5-20250529","doi-asserted-by":"crossref","first-page":"1610","DOI":"10.1001\/jama.288.13.1610","article-title":"Accuracy of hysteroscopy in the diagnosis of endometrial cancer and hyperplasia: A systematic quantitative review","volume":"288","author":"Clark","year":"2002","journal-title":"JAMA"},{"key":"R6-20250529","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1007\/s00404-014-3585-x","article-title":"Hysteroscopy in women with abnormal uterine bleeding: A meta-analysis on four major endometrial pathologies","volume":"291","author":"Gkrozou","year":"2015","journal-title":"Arch Gynecol Obstet"},{"key":"R7-20250529","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0002-9378(75)90984-9","article-title":"Hysteroscopic diagnosis of endometrial carcinoma. 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