{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:50:03Z","timestamp":1787071803941,"version":"build-2736575974"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>Gestational trophoblastic disease (GTD) typically occurs in women of reproductive age and is exceedingly rare in postmenopausal women. Hydatidiform mole is the most common form of GTD. The recommended management is total hysterectomy, as women over the age of 50 years have a higher risk of malignant transformation. Here, we report the case of massive molar pregnancy in a 52-year-old postmenopausal woman, complicated by hyperthyroidism and other comorbidities, with cultural and belief-related barriers influencing treatment decisions.<\/jats:p>","DOI":"10.4103\/jmh.jmh_247_25","type":"journal-article","created":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T19:01:12Z","timestamp":1765220472000},"page":"482-484","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["A Rare Case of Massive Molar Pregnancy in a Postmenopausal Woman: Challenges in Diagnosis and Management"],"prefix":"10.4103","volume":"16","author":[{"given":"Bayu Pratama","family":"Putra","sequence":"first","affiliation":[{"name":"Department of Obstetric and Gynecologi, Faculty of Medicine, Bosowa University, Makassar, South Sulawesi, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Desi Dwirosalia Ningsih","family":"Suparman","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Faculty of Medicine, Bosowa University, Makassar, South Sulawesi, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stazia","family":"Noija","sequence":"additional","affiliation":[{"name":"Medical Education Unit, Faculty of Medicine, Bosowa University, Makassar, South Sulawesi, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Faruk","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Faculty of Medicine, Bosowa University, Makassar, South Sulawesi, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,12,8]]},"reference":[{"key":"R1-20251212","doi-asserted-by":"crossref","first-page":"e00338","DOI":"10.1016\/j.crwh.2021.e00338","article-title":"Complete hydatidiform mole in a 52-year-old postmenopausal woman:A case report and literature review","volume":"31","author":"Wang","year":"2021","journal-title":"Case Rep Womens Health"},{"key":"R2-20251212","first-page":"e80315","article-title":"Complete hydatidiform mole in a 50-year-old postmenopausal woman:A case report","volume":"17","author":"Vural","year":"2025","journal-title":"Cureus"},{"key":"R3-20251212","doi-asserted-by":"crossref","first-page":"e000321","DOI":"10.1136\/bmjmed-2022-000321","article-title":"Advances in the diagnosis and early management of gestational trophoblastic disease","volume":"1","author":"Joyce","year":"2022","journal-title":"BMJ Med"},{"key":"R5-20251212","doi-asserted-by":"crossref","first-page":"2374289520987256","DOI":"10.1177\/2374289520987256","article-title":"Educational case:Hydatidiform molar pregnancy","volume":"8","author":"Lepore","year":"2021","journal-title":"Acad Pathol"},{"key":"R6-20251212","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.cca.2020.09.028","article-title":"Hyperthyroidism in molar pregnancy:b-HCG levels do not always reflect severity","volume":"511","author":"Chale-Matsau","year":"2020","journal-title":"Clin Chim Acta"},{"key":"R7-20251212","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13044-021-00092-3","article-title":"Hyperthyroidism in gestational trophoblastic disease \u2013A literature review","volume":"14","author":"Pereira","year":"2021","journal-title":"Thyroid Res"},{"key":"R8-20251212","doi-asserted-by":"crossref","first-page":"882","DOI":"10.18203\/2349-3933.ijam20233209","article-title":"The hyperthyroidism in gestational trophoblastic disease:A case report","volume":"10","author":"Hokman","year":"2023","journal-title":"Int J Adv Med"},{"key":"R9-20251212","first-page":"e22240","article-title":"Severe hyperthyroidism and complete hydatidiform mole in perimenopausal woman:Case report and literature review","volume":"14","author":"Da Silva Santos","year":"2022","journal-title":"Cureus"},{"key":"R10-20251212","first-page":"e34127","article-title":"Molar pregnancy-induced hyperthyroidism:The importance of early recognition and management","volume":"15","author":"Alhassan","year":"2023","journal-title":"Cureus"},{"key":"R11-20251212","doi-asserted-by":"crossref","first-page":"bcr2012006213","DOI":"10.1136\/bcr-2012-006213","article-title":"Molar pregnancy in postmenopausal women:A rare phenomenon","author":"Mehrotra","year":"2012","journal-title":"BMJ Case Rep. 2012"}],"updated-by":[{"DOI":"10.4103\/jmh.jmh_48_26","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000}}],"container-title":["Journal of Mid-life Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jmh.jmh_247_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:56:21Z","timestamp":1787068581000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jmh.jmh_247_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jmh.jmh_247_25","relation":{},"ISSN":["0976-7800","0976-7819"],"issn-type":[{"value":"0976-7800","type":"print"},{"value":"0976-7819","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"2025-09-20","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-23","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}