{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:31:00Z","timestamp":1787070660465,"version":"build-2736575974"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and Hypothesis:<\/jats:title>\n                    <jats:p>The aims of this study were to define long-term anatomic outcome, satisfaction rate, and reasons for disappointment and regret in a group of patients with advanced pelvic organ prolapse who underwent LeFort colpocleisis (LFC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      This was a retrospective, single-center, cohort study including consecutive patients who underwent LFC from 2007 to 2021. All patients had surgery involving vaginal hysterectomy and anti-incontinence procedure where clinically indicated. All patients were examined 3 months after surgery. A cross-sectional telephone survey was performed in 2022 using the Patient Global Impression of Severity (PGI-S), Patient Global Impression of Improvement (PGI-I), and Patient Global Impression of Change (PGI-C) questionnaires, as well as the Decision Regret Scale. Student\u2019s\n                      <jats:italic toggle=\"yes\">t<\/jats:italic>\n                      -test, Fisher\u2019s Chi-square test, and univariable logistic regression analysis were carried out.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      One hundred and forty-one patients (mean age 74.95 \u00b1 6.25 years) were included. The mean preoperative POP Quantification C\/D point was +6 (\u00b12.7). In 86 (60.99%) patients, a hysterectomy and in 56 (39.71%), a mid-urethral synthetic sling was performed. At 3-month follow-up, there was one prolapse recurrence (0.71%) and no case of regret of sexual function loss. In the long term, 28 patients died, and 69 patients were interviewed through telephone (follow-up 61.65 months). The mean PGI-S, PGI-I, and PGI-C scores were 1.42 (\u00b10.81), 1.93 (\u00b11.45), and 5.91 (\u00b11.69) respectively, and no patient declared regret about vaginal intercourse loss. Preoperative and postoperative persistent or\n                      <jats:italic toggle=\"yes\">de novo<\/jats:italic>\n                      mixed UI appeared to be related to decreased satisfaction and regret post-LFC (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.0021).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>\n                      LFC is a valuable, easy-to-perform technique with long-lasting results and decreased postoperative anti-incontinence rates. However,\n                      <jats:italic toggle=\"yes\">de novo<\/jats:italic>\n                      or persistent urinary incontinence appears to be related to decreased satisfaction rates.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jmh.jmh_38_24","type":"journal-article","created":{"date-parts":[[2024,10,17]],"date-time":"2024-10-17T10:06:43Z","timestamp":1729159603000},"page":"153-160","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["LeFort Colpocleisis: Unmet Expectations about Correction of Urinary Symptoms Are Related to Disappointment and Regret"],"prefix":"10.4103","volume":"15","author":[{"given":"Themistoklis","family":"Mikos","sequence":"first","affiliation":[{"name":"1Department of Obstetrics and Gynecoloogy, Papageorgiou General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofia","family":"Tsiapakidou","sequence":"additional","affiliation":[{"name":"1Department of Obstetrics and Gynecoloogy, Papageorgiou General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Lioupis","sequence":"additional","affiliation":[{"name":"1Department of Obstetrics and Gynecoloogy, Papageorgiou General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christos","family":"Anthoulakis","sequence":"additional","affiliation":[{"name":"1Department of Obstetrics and Gynecoloogy, Papageorgiou General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iakovos","family":"Theodoulidis","sequence":"additional","affiliation":[{"name":"1Department of Obstetrics and Gynecoloogy, Papageorgiou General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grigoris F.","family":"Grimbizis","sequence":"additional","affiliation":[{"name":"1Department of Obstetrics and Gynecoloogy, Papageorgiou General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,10,17]]},"reference":[{"key":"R1-20241019","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1097\/AOG.0000000000000286","article-title":"Lifetime risk of stress urinary incontinence or pelvic organ prolapse surgery","volume":"123","author":"Wu","year":"2014","journal-title":"Obstet Gynecol"},{"key":"R2-20241019","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1002\/nau.22922","article-title":"An International Urogynecological Association (IUGA)\/International Continence Society (ICS) joint report on the terminology for female Pelvic organ prolapse (POP)","volume":"35","author":"Haylen","year":"2016","journal-title":"Neurourol Urodyn"},{"key":"R3-20241019","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1002\/nau.20798","article-title":"An International Urogynecological Association (IUGA)\/International Continence Society (ICS) joint report on the terminology for female pelvic floor dysfunction","volume":"29","author":"Haylen","year":"2010","journal-title":"Neurourol Urodyn"},{"key":"R4-20241019","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s00192-010-1324-9","article-title":"An International Urogynecological Association (IUGA)\/International Continence Society (ICS) joint terminology and classification of the complications related directly to the insertion of prostheses (meshes, implants, tapes) and grafts in female pelvic floor surgery","volume":"22","author":"Haylen","year":"2011","journal-title":"Int Urogynecol J"},{"key":"R5-20241019","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1007\/s00192-011-1441-0","article-title":"LeFort colpocleisis and stress incontinence:Weighing the risk of voiding dysfunction with sling placement","volume":"22","author":"Smith","year":"2011","journal-title":"Int Urogynecol J"},{"key":"R6-20241019","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1007\/s00192-016-3236-9","article-title":"Enlightening the mechanisms of POP recurrence after LeFort colpocleisis. 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