{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:30:47Z","timestamp":1787070647707,"version":"build-2736575974"},"reference-count":13,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>We report the case of a 51-year-old female with an unusual presentation of a cutaneous granular cell tumor (GCT) on the lower back. The lesion was asymptomatic, well-defined, and firm, with an initial clinical differential of dermatofibroma, pilomatricoma, or leiomyoma. Histopathological examination revealed a dermal tumor composed of large polygonal cells with granular eosinophilic cytoplasm and uniform nuclei, without atypia or necrosis. Immunohistochemistry confirmed the diagnosis with strong S100 and CD68 positivity. Due to tumor extension tumor extension to the deep resection margin, close follow-up was advised. Accurate diagnosis of cutaneous GCTs relies on histopathology and immunohistochemistry, as clinical and dermoscopic findings are often nonspecific. Complete surgical excision is the primary treatment, with a generally favorable prognosis. Awareness of malignant potential and proper surgical management is crucial for optimal outcomes.<\/jats:p>","DOI":"10.4103\/jmh.jmh_62_25","type":"journal-article","created":{"date-parts":[[2025,6,23]],"date-time":"2025-06-23T06:00:10Z","timestamp":1750658410000},"page":"218-220","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Cutaneous Granular Cell Tumor in a Middle-aged Woman: Clinicopathological Insights from a Rare Schwannian Neoplasm"],"prefix":"10.4103","volume":"16","author":[{"given":"Seetu","family":"Palo","sequence":"first","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, All India Institute of Medical Sciences, Bibinagar, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Mishra","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, All India Institute of Medical Sciences, Bibinagar, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kailas Anteshwar","family":"Mulsange","sequence":"additional","affiliation":[{"name":"Department of Dermatology, All India Institute of Medical Sciences, Bibinagar, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,6,23]]},"reference":[{"key":"R1-20250628","doi-asserted-by":"crossref","first-page":"152865","DOI":"10.1016\/j.prp.2020.152865","article-title":"Granular cell tumor a study of 42 cases and systemic review of the literature","volume":"216","author":"Mobarki","year":"2020","journal-title":"Pathol Res Pract"},{"key":"R2-20250628","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1186\/s13000-015-0357-2","article-title":"Primary cutaneous malignant granular cell tumor: A case report in China and review of the literature","volume":"10","author":"Liu","year":"2015","journal-title":"Diagn 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tumors of soft tissue: A clinicopathologic study of 50 patients","volume":"148","author":"Stemm","year":"2017","journal-title":"Am J Clin Pathol"},{"key":"R7-20250628","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1016\/j.jaad.2017.09.062","article-title":"Epidemiology of malignant cutaneous granular cell tumors: A US population-based cohort analysis using the Surveillance, Epidemiology, and End Results (SEER) database","volume":"78","author":"Mirza","year":"2018","journal-title":"J Am Acad Dermatol"},{"key":"R8-20250628","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1097\/PAS.0000000000001992","article-title":"Molecular characterization of multifocal granular cell tumors","volume":"47","author":"Dehner","year":"2023","journal-title":"Am J Surg Pathol"},{"key":"R9-20250628","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.path.2017.01.008","article-title":"Cutaneous malignant peripheral nerve sheath 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