{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:35:26Z","timestamp":1787070926385,"version":"build-2736575974"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>Adenofibroma of the cervix is an extremely rare benign Mullerian mixed tumor, which contains both benign epithelial and mesenchymal tissue. The WHO 2020 classification of the female genital tract does not even include adenofibroma as a separate entity. A postmenopausal lady in her mid-50s presented with bleeding per vagina. On examination, there were multiple cervical polyps. Histopathology of cervical polyps suggested adenofibroma of the cervix due to the absence of mitotic figures and cellular atypia. Sometimes even well-differentiated adenosarcomas can be misdiagnosed as adenofibroma. Immunohistochemistry markers help in differentiating adenosarcoma from adenofibroma. There are no typical clinical or imaging characteristics that strongly suggest the diagnosis. Although adenofibroma is a benign tumor; still it has been found to invade the myometrium and pelvic veins, relapse, and metastasize. It is crucial to perform a detailed histopathological examination of all the cervical tumors not only to exclude malignant lesions but also to exclude adenofibroma regardless of clinical symptoms.<\/jats:p>","DOI":"10.4103\/jmh.jmh_71_25","type":"journal-article","created":{"date-parts":[[2025,9,5]],"date-time":"2025-09-05T13:01:02Z","timestamp":1757077262000},"page":"321-323","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Cervical Adenofibroma: A Rare Cause for Postmenopausal Bleeding"],"prefix":"10.4103","volume":"16","author":[{"given":"Navdeep","family":"Kaur","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology, PGIMER Satellite Centre, Sangrur, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akanksha","family":"Agarwal","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, AIIMS, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bharti","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, PGIMER, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nalini","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Cytology and Gynaecological Pathology, PGIMER, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,9,5]]},"reference":[{"key":"R1-20250908","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1055\/a-1545-4279","article-title":"2020 WHO classification of female genital tumors","volume":"81","author":"H\u00f6hn","year":"2021","journal-title":"Geburtshilfe Frauenheilkd"},{"issue":"Suppl 1","key":"R2-20250908","doi-asserted-by":"crossref","first-page":"S78","DOI":"10.1038\/modpathol.2015.137","article-title":"A practical approach to the diagnosis of mixed epithelial and mesenchymal tumours of the uterus","volume":"29","author":"McCluggage","year":"2016","journal-title":"Mod Pathol"},{"key":"R3-20250908","doi-asserted-by":"crossref","first-page":"3000605221125525","DOI":"10.1177\/03000605221125525","article-title":"Cervical adenofibroma without clinical symptoms:Report of a rare case","volume":"50","author":"Li","year":"2022","journal-title":"J Int Med Res"},{"key":"R4-20250908","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s004040100208","article-title":"Uterine cervical adenofibroma associated with Turner's syndrome in a young woman","volume":"267","author":"Ishiko","year":"2002","journal-title":"Arch Gynecol Obstet"},{"key":"R5-20250908","first-page":"308464","article-title":"Adenofibroma in a young patient:A rare entity in an uncommon age","volume":"2013","author":"Maciel","year":"2013","journal-title":"Case Rep Obstet Gynecol"},{"key":"R6-20250908","first-page":"524","article-title":"Papillary adenofibroma of cervix","volume":"97","author":"Mohan","year":"1999","journal-title":"J Indian Med Assoc"},{"key":"R7-20250908","first-page":"135","article-title":"Papillary adenofibroma of the uterine cervix. 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An unusual tumour of the cervix","volume":"24","author":"Candes","year":"1987","journal-title":"Indian J Cancer"},{"key":"R11-20250908","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.tjog.2012.04.022","article-title":"Adenofibroma of the uterine cervix coexistent with endometriosis","volume":"51","author":"Chu","year":"2012","journal-title":"Taiwan J Obstet Gynecol"},{"key":"R12-20250908","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1097\/PAS.0b013e318181a80d","article-title":"Mullerian adenosarcoma:A clinicopathologic and immunohistochemical study of 55 cases challenging the existence of adenofibroma","volume":"33","author":"Gallardo","year":"2009","journal-title":"Am J Surg Pathol"}],"container-title":["Journal of Mid-life Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jmh.jmh_71_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:39:00Z","timestamp":1787067540000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jmh.jmh_71_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":12,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jmh.jmh_71_25","relation":{},"ISSN":["0976-7800","0976-7819"],"issn-type":[{"value":"0976-7800","type":"print"},{"value":"0976-7819","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"2025-03-24","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-02","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}