{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:36:27Z","timestamp":1787841387726,"version":"build-2784847793"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:sec>\n                    <jats:title>Aims:<\/jats:title>\n                    <jats:p>The dosimetric leaf gap (DLG) is a parameter for correcting radiation transmission through the round leaf end of multileaf collimators. The purpose of this study was to determine and investigate the optimal DLG correction factor for 6 MV volumetric-modulated arc radiotherapy (VMAT) plan dose calculations in Mobius3D.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Seventeen VMAT plans were selected for the DLG correction factor optimization process. The optimal DLG correction factor was defined as the minimum difference between the measured dose and the Mobius3D-calculated dose on the Mobius Verification Phantom\u2122 with different DLG correction factors. Subsequently, the optimal DLG correction factor was applied for Mobius3D dose calculation, and accuracy was assessed by comparing the measured and calculated doses. For verification and validation, the 17 previous plans and 10 newly selected plans underwent Mobius3D calculations with the optimal DLG correction factor, and gamma analysis was performed to compare them to the treatment planning system (TPS). Gamma analysis was also performed between the electronic portal imaging device (EPID) and the TPS for cross-comparison between systems.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The DLG correction factor was optimized to \u22121.252, which reduced the average percentage differences between measured and Mobius3D-calculated doses from 2.23% \u00b11.21% to 0.03% \u00b11.82%. The cross-comparison between Mobius3D\/TPS and EPID\/TPS revealed a similar trend in gamma passing rate (&gt;95%) in both the verification and validation plans.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The DLG correction factor strongly influences the accuracy of Mobius3D-calculated doses. Applying the optimal DLG correction factor can increase dose agreement and gamma passing rate between calculation and delivered doses of VMAT plans, which emphasizes the importance of optimizing this factor during the commissioning process.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jmp.jmp_11_24","type":"journal-article","created":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T09:25:58Z","timestamp":1719912358000},"page":"261-269","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Investigating the Dosimetric Leaf Gap Correction Factor of Mobius3D Dose Calculation for Volumetric-modulated Arc Radiotherapy Plans"],"prefix":"10.4103","volume":"49","author":[{"given":"Thitipong","family":"Sawapabmongkon","sequence":"first","affiliation":[{"name":"Division of Radiation Oncology, Department of Diagnostic and Therapeutic Radiology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pimolpun","family":"Changkaew","sequence":"additional","affiliation":[{"name":"Division of Radiation Oncology, Department of Diagnostic and Therapeutic Radiology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chanon","family":"Puttanawarut","sequence":"additional","affiliation":[{"name":"Chakri Naruebodindra Medical Institute, Mahidol University, Samut Prakan, Thailand"},{"name":"Department of Clinical Epidemiology and Biostatistics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Puangpen","family":"Tangboonduangjit","sequence":"additional","affiliation":[{"name":"Division of Radiation Oncology, Department of Diagnostic and Therapeutic Radiology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suphalak","family":"Khachonkham","sequence":"additional","affiliation":[{"name":"Division of Radiation Oncology, Department of Diagnostic and Therapeutic Radiology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,6,25]]},"reference":[{"key":"R1-20240906","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1186\/1748-717X-7-111","article-title":"Adosimetric comparison of 3D conformal versus intensity modulated versus volumetric arc radiation therapy for muscle invasive bladder cancer","volume":"7","author":"Foroudi","year":"2012","journal-title":"Radiat Oncol"},{"key":"R2-20240906","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1186\/s13014-017-0812-1","article-title":"Dosimetric comparison of helical tomotherapy, VMAT, fixed-field IMRT and 3D-conformal radiotherapy for stage I-II nasal natural killer T-cell lymphoma","volume":"12","author":"Liu","year":"2017","journal-title":"Radiat Oncol"},{"key":"R3-20240906","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1007\/s00066-016-1020-x","article-title":"Comparison of dosimetric parameters and toxicity in esophageal cancer patients undergoing 3D conformal radiotherapy or VMAT","volume":"192","author":"M\u00fcnch","year":"2016","journal-title":"Strahlenther Onkol"},{"key":"R4-20240906","first-page":"e53","article-title":"Tolerance limits and methodologies for IMRT measurement-based verification QA:Recommendations of AAPM task group no","volume":"45","author":"Miften","year":"2018","journal-title":"218. 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