{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:32:04Z","timestamp":1787776324325,"version":"build-2784847793"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2020,4]]},"abstract":"\n Purpose:<\/jats:title>\n \n The aim of this study is to estimate delivered radiation doses inside planning tumor volume (PTV) using the\n in vivo<\/jats:italic>\n (mid-plane dose) measurement and transit measurement methods in gynecological malignancy patients undergoing three-dimensional conformal radiotherapy (3DCRT) using calibrated ionization chambers.\n <\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n \n Six patients with histopathologically proven carcinoma of the cervix or endometrium were planned with four-field 3DCRT to the pelvic site. Isocenter was at the geometric mid-plane of PTV with a dose prescription of 50 Gy in 25 fractions. Clinical mid-plane dose (D\n iso,\n Transit)<\/jats:italic>\n estimates were done in one method (transit) using the FC-65 positioned at electronic portal imaging device level. In another method, a repeat computerized tomography scan was performed (at the 11\n th<\/jats:sup>\n fraction) using CC-13 having a protective cap in the vaginal cavity for\n in vivo<\/jats:italic>\n measurements (D\n in vivo<\/jats:italic>\n ). Simultaneous measurements were performed with the two chambers from the 11\n th<\/jats:sup>\n fraction onward at least 3\u20134 times during the remaining course of treatment.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The agreement of mean doses from these two described methods and treatment planning system reference doses was in the range of \u22124.4 \u00b1 1.1% (minimum) to \u22120.3 \u00b1 2.0% (maximum) and \u22124.0 \u00b1 1.7% (minimum) to 1.9 \u00b1 2.4% for D\n in\n vivo and<\/jats:italic>\n D\n iso,\n Transit<\/jats:italic>\n , respectively, which are an acceptable range of daily radiation dose delivery.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n The fundamental importance of this study lies in simultaneous validation of delivered dose in real time with two methods. A study in this small number of patients has given the confidence to apply transit measurements for quality assurance on a routine basis as an accepted clinical dosimetry for the selected patients.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jmp.jmp_3_20","type":"journal-article","created":{"date-parts":[[2020,7,20]],"date-time":"2020-07-20T07:38:15Z","timestamp":1595230695000},"page":"123-129","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Simultaneous Measurement of In vivo and Transit Mid-Plane Doses with Ionization Chambers in Gynecological Malignancy Patients Undergoing Three-Dimensional Conformal Radiotherapy"],"prefix":"10.4103","volume":"45","author":[{"given":"Putha Suman","family":"Kumar","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology, Kasturba Medical College (A constituent institution of Manipal Academy of Higher Education, Manipal), Mangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Challapalli","family":"Srinivas","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Kasturba Medical College (A constituent institution of Manipal Academy of Higher Education, Manipal), Mangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B. 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