{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T09:58:57Z","timestamp":1790330337186,"version":"4.1.0"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>The purpose of this study was to describe the planning, dosimetric evaluation, quality assurance (QA), and clinical implementation of a feathered junction technique for low-dose total body irradiation (TBI) using a common coordinate system and fictive field approach with an extended source-to-skin distance (SSD) anteroposterior\/posteroanterior (AP\/PA) couch-based linear accelerator technique.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Six patients treated with low-dose TBI for hematopoietic stem cell transplant conditioning were included. Two patients had aplastic anemia (2 Gy\/1 fraction), two had myelodysplastic syndrome (4 Gy\/2 fractions), and two had leukemia (2 Gy\/1 fraction). Computed tomography (CT) simulation was performed in head-first supine and feet-first supine positions using a full-body Vac-Lok system, with a pelvic fiducial marker defining a common coordinate origin. Treatment planning was performed in the Monaco treatment planning system for an Elekta Synergy linear accelerator (6 MV, MLCi2). An extended-SSD AP\/PA technique with jaw-based feathered junctions was used. Dosimetric evaluation included target coverage, junction dose characteristics, and organ-at-risk doses. QA included ionization chamber measurements and cone-beam CT verification.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Adequate target coverage was achieved. The mean planning target volume D95% and V95% were 92.9% \u00b12.05% and 94.03% \u00b11.47%, respectively. The mean maximum dose was 115.51% \u00b10.32%, mainly in peripheral regions. The mean lung doses were 103% \u00b11.2% and 104% \u00b10.8%, and kidney doses were 102% \u00b10.96% and 101.5% \u00b11.35%. Junction doses ranged from 102.5% \u00b10.5% to 105.5% \u00b10.6%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The technique achieved acceptable dose homogeneity and controlled junction doses. It provides a reproducible and feasible approach for low-dose TBI using standard linear accelerator infrastructure without organ shielding.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jmp.jmp_87_26","type":"journal-article","created":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T13:00:57Z","timestamp":1790168457000},"page":"525-535","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Fictive Field-based Feathering for Extended-SSD Total Body Irradiation: A Single-institution Planning and Dosimetric Analysis"],"prefix":"10.4103","volume":"51","author":[{"given":"Vijay Kumar","family":"Mogulagani","sequence":"first","affiliation":[{"name":"Department of Physics, University College of Science, Osmania University, Banjara Hills, Hyderabad, Telangana, India"},{"name":"Department of Radiotherapy, Omega Hospitals, Banjara Hills, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohan Raj","family":"Uthiran","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy, Omega Hospitals, Banjara Hills, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben Johnson","family":"Varghese","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy, Omega Hospitals, Banjara Hills, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siva Kumar","family":"Radhakrishnan","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy, Omega Hospitals, Banjara Hills, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lakshmana","family":"Perumal","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy, Omega Hospitals, Banjara Hills, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madhuri","family":"Dumpala","sequence":"additional","affiliation":[{"name":"Department of Physics, University College of Science, Osmania University, Banjara Hills, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,9,23]]},"reference":[{"key":"R1-20260925","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/0360-3016(82)90083-9","article-title":"Marrow transplantation for acute nonlymphoblastic leukemic in first remission using fractionated or single-dose irradiation","volume":"8","author":"Thomas","year":"1982","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"R2-20260925","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1007\/BF03038482","article-title":"Total-body irradiation before bone marrow transplantation for acute leukemia in first or second complete remission. Results and prognostic factors in 326 consecutive patients","volume":"174","author":"Belkac\u00e9mi","year":"1998","journal-title":"Strahlenther Onkol"},{"key":"R4-20260925","author":"Van Dyk","journal-title":"The physical aspects of total and half body photon irradiation"},{"key":"R5-20260925","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0167-8140(87)80197-4","article-title":"Total body irradiation \u2013 Review of treatment techniques in Europe","volume":"9","author":"Quast","year":"1987","journal-title":"Radiother Oncol"},{"key":"R6-20260925","doi-asserted-by":"crossref","first-page":"3214","DOI":"10.1118\/1.2044428","article-title":"Feasibility study of helical tomotherapy for total body or total marrow irradiation","volume":"32","author":"Hui","year":"2005","journal-title":"Med Phys"},{"key":"R7-20260925","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/s13014-016-0625-7","article-title":"Total body irradiation with volumetric modulated arc therapy: Dosimetric data and first clinical experience","volume":"11","author":"Springer","year":"2016","journal-title":"Radiat Oncol"},{"key":"R9-20260925","first-page":"71","article-title":"CT-based analysis of dose homogeneity in total body irradiation using lateral beam","volume":"5","author":"Hui","year":"2004","journal-title":"J Appl Clin Med Phys"},{"key":"R10-20260925","doi-asserted-by":"crossref","first-page":"192","DOI":"10.4103\/jrcr.jrcr_52_22","article-title":"Evaluation of total body irradiation with three-dimensional conformal radiotherapy: A pilot study to establish an institutional protocol","volume":"14","author":"Anumanthraj","year":"2023","journal-title":"J Radiat Cancer Res"},{"key":"R11-20260925","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.ijrobp.2018.04.071","article-title":"Total body irradiation: Guidelines from the international lymphoma radiation oncology group (ILROG)","volume":"101","author":"Wong","year":"2018","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"R12-20260925","first-page":"1283","article-title":"Total body irradiation with lung dose-reduction does not improve hematopoietic cell homing to bone marrow during allogeneic transplantation","volume":"15","author":"Singh","year":"2009","journal-title":"Biol Blood Marrow Transplant"},{"key":"R13-20260925","doi-asserted-by":"crossref","first-page":"105720","DOI":"10.1016\/j.ejmp.2026.105720","article-title":"Novel methods to verify dose distribution at the junction region in large-field helical total body Irradiation","volume":"142","author":"Samuvel","year":"2026","journal-title":"Phys Med"}],"container-title":["Journal of Medical Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jmp.jmp_87_26","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T09:01:06Z","timestamp":1790326866000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jmp.jmp_87_26"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/jmp.jmp_87_26","relation":{},"ISSN":["0971-6203","1998-3913"],"issn-type":[{"value":"0971-6203","type":"print"},{"value":"1998-3913","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"2026-04-20","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-28","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}