{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T17:24:09Z","timestamp":1787765049482,"version":"build-2784847793"},"reference-count":33,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"Abstract<\/jats:title>\n \n Background:<\/jats:title>\n Hypertensive disorder of pregnancy (HDP) comprise chronic hypertension, gestational hypertension, preeclampsia\/eclampsia, and preeclampsia superimposed on chronic hypertension. HDP complicate up to 10% of pregnancies worldwide and carry significant risks of maternal and perinatal morbidity and mortality. The aim of this study was to evaluate the derangement and characteristics of brachial artery flow-mediated dilation (BAFMD) in women with HDP.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n \n The BAFMD of the right brachial artery of 80 women with HDP (pregnant HDP), 80 normotensive pregnant women (pregnant non-HDP), and 80 healthy nonpregnant women (nonpregnant controls) was evaluated with B-mode ultrasound. The age, blood pressure, body mass index (BMI), brachial artery diameter, and BAFMD of the participants were compared.\n P<\/jats:italic>\n \u2264 0.05 was statistically significant.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The pregnant HDP group had significantly lower mean BAFMD compared to pregnant non-HDP and nonpregnant controls (6.9% \u00b1 2.53% vs. 8.32% \u00b1 3.4% vs. 9.4% \u00b1 2.68%;\n P<\/jats:italic>\n < 0.001). There was no significant difference between the mean BAFMD of the pregnant HDP subgroups: preeclampsia (5.81% \u00b1 1.7%) versus gestational hypertension (6.43% \u00b1 3.02%);\n P<\/jats:italic>\n = 0.57. BAFMD diminished with advancing gestational age in both the pregnant HDP and pregnant non-HDP groups. On regression analysis, BAFMD was a poor marker for HDP, while BMI was an independent predictor for HDP.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Even though HDP were associated with significantly diminished BAFMD, it was not a good marker for HDP.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jmu.jmu_10_23","type":"journal-article","created":{"date-parts":[[2024,1,3]],"date-time":"2024-01-03T07:00:23Z","timestamp":1704265223000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Flow-mediated Dilation of the Brachial Artery in Women with Hypertensive Disorders of Pregnancy"],"prefix":"10.4103","author":[{"given":"Babatunde Opeyemi","family":"Oguntade","sequence":"first","affiliation":[{"name":"Department of Radiology, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Osun, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bolanle Olubunmi","family":"Ibitoye","sequence":"additional","affiliation":[{"name":"Department of Radiology, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Osun, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olufemiwa Niyi","family":"Makinde","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Osun, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bukunmi Michael","family":"Idowu","sequence":"additional","affiliation":[{"name":"Department of Radiology, Union Diagnostics and Clinical Services Plc, Lagos, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tolulope Adebayo","family":"Okedere","sequence":"additional","affiliation":[{"name":"Department of Radiology, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Osun, 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