{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T17:52:01Z","timestamp":1788457921833,"version":"build-2803163510"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2024,1,30]],"date-time":"2024-01-30T00:00:00Z","timestamp":1706572800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:p>Thyroid hemiagenesis (THA) is a rare congenital abnormality in which one of the thyroid lobes fails to develop normally. The prevalence rates range from 0.02% to 0.25%, with no gender preponderance and most commonly involve the left lobe. We report a case of left THA in a 37-year-old female that was found incidentally during total thyroidectomy for right papillary thyroid carcinoma. Most patients with THA are asymptomatic, however, may have subclinically raised thyroid-stimulating hormone levels or be predisposed to developing thyroid disorders such as nodular goiter, hyperthyroidism, Grave\u2019s disease, Hashimoto\u2019s thyroiditis, hyperparathyroidism, or malignancy. Usual imaging techniques such as ultrasonography, computed tomography, and magnetic resonance imaging allow the confirmation of diagnosis and provide clearer glandular and regional visualization. Additional modalities such as thyroid scintigraphy enable the functional assessment and identification of any suspicious nodules and aid in decision-making. THA is a very uncommon condition and the diagnosis is primarily made through imaging. Clinicians should be aware that this condition exists along with documented associations of concomitant thyroid disorders and malignancy.<\/jats:p>","DOI":"10.4103\/jmu.jmu_32_23","type":"journal-article","created":{"date-parts":[[2024,1,30]],"date-time":"2024-01-30T10:02:36Z","timestamp":1706608956000},"page":"352-354","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Thyroid Hemiagenesis: An Incidental Discovery during Treatment for Papillary Thyroid Carcinoma"],"prefix":"10.4103","volume":"32","author":[{"given":"Chang Haur","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Surgery, Queen Elizabeth II Hospital, Ministry of Health Malaysia, Kota Kinabalu, Sabah, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yazid Pol","family":"Ong","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Queen Elizabeth Hospital, Ministry of Health Malaysia, Kota Kinabalu, Sabah, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Firdaus","family":"Hayati","sequence":"additional","affiliation":[{"name":"Department of Surgery, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Zahid Abdul","family":"Muien","sequence":"additional","affiliation":[{"name":"Department of Radiology, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siti Zubaidah","family":"Sharif","sequence":"additional","affiliation":[{"name":"Department of Surgery, Queen Elizabeth II Hospital, Ministry of Health Malaysia, Kota Kinabalu, Sabah, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,1,30]]},"reference":[{"key":"R2-20260724","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1089\/thy.2007.0408","article-title":"Prevalence of thyroid hemiagenesis in an asymptomatic schoolchildren population","volume":"18","author":"Korpal-Szczyrska","year":"2008","journal-title":"Thyroid"},{"key":"R3-20260724","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1007\/s12020-008-9095-5","article-title":"Clinical and epidemiological characteristics of thyroid hemiagenesis: Ultrasound screening in patients with thyroid disease and normal population","volume":"33","author":"Gursoy","year":"2008","journal-title":"Endocrine"},{"key":"R4-20260724","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1089\/thy.2016.0662","article-title":"Prevalence and characterization of thyroid hemiagenesis in Japan: The Fukushima health management survey","volume":"27","author":"Suzuki","year":"2017","journal-title":"Thyroid"},{"key":"R5-20260724","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1530\/EJE-09-0590","article-title":"Increased risk of thyroid pathology in patients with thyroid hemiagenesis: Results of a large cohort case-control study","volume":"162","author":"Ruchala","year":"2010","journal-title":"Eur J Endocrinol"},{"key":"R6-20260724","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1089\/thy.1999.9.1075","article-title":"Thyroid hemiagenesis in an endemic goiter area diagnosed by ultrasonography: Report of sixteen patients","volume":"9","author":"Mikosch","year":"1999","journal-title":"Thyroid"},{"key":"R7-20260724","first-page":"829712","article-title":"Thyroid hemiagenesis associated with hyperthyroidism","volume":"2015","author":"Gurleyik","year":"2015","journal-title":"Case Rep Otolaryngol"},{"key":"R8-20260724","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1007\/s00005-016-0393-y","article-title":"Does TSH trigger the anti-thyroid autoimmune processes? Observation on a large cohort of naive patients with thyroid hemiagenesis","volume":"64","author":"Szczepanek-Parulska","year":"2016","journal-title":"Arch Immunol Ther Exp (Warsz)"},{"key":"R9-20260724","first-page":"e22401","article-title":"Thyroid hemiagenesis: Narrative review and clinical implications","volume":"14","author":"Lesi","year":"2022","journal-title":"Cureus"},{"key":"R10-20260724","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1089\/10507250150500612","article-title":"Overexpression of epidermal growth factor and epidermal growth factor-receptor mRNAs in dyshormonogenetic goiters","volume":"11","author":"Pedrinola","year":"2001","journal-title":"Thyroid"}],"container-title":["Journal of Medical Ultrasound"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jmu.jmu_32_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:40:49Z","timestamp":1787067649000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jmu.jmu_32_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,30]]},"references-count":9,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jmu.jmu_32_23","relation":{},"ISSN":["0929-6441","2212-1552"],"issn-type":[{"value":"0929-6441","type":"print"},{"value":"2212-1552","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,30]]},"assertion":[{"value":"2023-03-25","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-20","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}