{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:20:38Z","timestamp":1787772038538,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Lemmel\u2019s syndrome is a bile duct disease caused by periampullary duodenal diverticula that develop within 2\u20133 cm of the Vater papilla. This disease manifests itself as nonobstructive jaundice. In most cases, duodenal diverticula do not cause disease, and only in a small percentage of patients, diverticula cause biliary tract obstruction by extrinsic compression. If the compression is severe, in the long term, it can become complicated with lithiasis and cholangitis. Diagnosis is very difficult, and recurrent biliary symptoms must be directly related to the compression of the duodenal diverticula. Imaging is essential for differential diagnosis and includes conventional contrast radiographs, endoscopic retrograde cholangiopancreatography, computed tomography, and magnetic resonance imaging. The investigations show the dilation of the intra- and extra-hepatic bile ducts in the absence of lithiasis or main pancreatic duct dilatation, compressed by the diverticula, which most frequently originate from the medial wall of the second duodenal tract. The treatment of choice is surgical with removal of the diverticula. Failure to diagnose can cause serious health complications for the patient.<\/jats:p>","DOI":"10.4103\/jmu.jmu_39_22","type":"journal-article","created":{"date-parts":[[2024,3,22]],"date-time":"2024-03-22T05:01:24Z","timestamp":1711083684000},"page":"79-82","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["Lemmel\u2019s Syndrome: Lesson Based on a Case Report"],"prefix":"10.4103","volume":"32","author":[{"given":"Renato","family":"Farina","sequence":"first","affiliation":[{"name":"Department of Medical Surgical Sciences and Advanced Technologies \u201cG.F. Ingrassia\u201d, University of Catania, Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pietro Valerio","family":"Foti","sequence":"additional","affiliation":[{"name":"Department of Medical Surgical Sciences and Advanced Technologies \u201cG.F. Ingrassia\u201d, University of Catania, Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana","family":"Ilardi","sequence":"additional","affiliation":[{"name":"Department of Medical Surgical Sciences and Advanced Technologies \u201cG.F. Ingrassia\u201d, University of Catania, Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Basile","sequence":"additional","affiliation":[{"name":"Department of Medical Surgical Sciences and Advanced Technologies \u201cG.F. Ingrassia\u201d, University of Catania, Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,1,19]]},"reference":[{"key":"R1-20240830","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1159\/000196978","article-title":"The clinical significance of the duodenal diverticula","volume":"46","author":"Lemmel","year":"1934","journal-title":"Arch Verdauungskrht"},{"key":"R2-20240830","doi-asserted-by":"crossref","first-page":"874","DOI":"10.3346\/jkms.2014.29.6.874","article-title":"Lemmel's syndrome, an unusual cause of abdominal pain and jaundice by impacted intradiverticular enterolith:Case report","volume":"29","author":"Kang","year":"2014","journal-title":"J Korean Med Sci"},{"key":"R3-20240830","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/j.clinre.2012.05.002","article-title":"Lemmel's syndrome as a rare cause of obstructive jaundice","volume":"36","author":"Rouet","year":"2012","journal-title":"Clin Res Hepatol Gastroenterol"},{"key":"R4-20240830","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1007\/s005950050117","article-title":"Endoscopic manometry of the sphincter of Oddi in patients with Lemmel's syndrome","volume":"28","author":"Tomita","year":"1998","journal-title":"Surg Today"},{"key":"R5-20240830","doi-asserted-by":"crossref","first-page":"2805","DOI":"10.1007\/s10620-022-07571-z","article-title":"Debris-Filled duodenal diverticulum and Lemmel's syndrome","volume":"67","author":"Zorzetti","year":"2022","journal-title":"Dig Dis Sci"},{"key":"R6-20240830","doi-asserted-by":"crossref","first-page":"205","DOI":"10.3109\/00365528909093038","article-title":"Beta-glucuronidase activity in the bile of gallstone patients both with and without duodenal diverticula","volume":"24","author":"Skar","year":"1989","journal-title":"Scand J Gastroenterol"},{"key":"R7-20240830","doi-asserted-by":"crossref","first-page":"2998","DOI":"10.1016\/j.radcr.2021.07.004","article-title":"Superior mesenteric artery syndrome (Wilkie syndrome) with unusual clinical onset:Description of a rare case","volume":"16","author":"Farina","year":"2021","journal-title":"Radiol Case Rep"},{"key":"R8-20240830","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.jviscsurg.2013.04.006","article-title":"Management of complicated duodenal diverticula","volume":"150","author":"Oukachbi","year":"2013","journal-title":"J Visc Surg"},{"key":"R9-20240830","first-page":"e16959","article-title":"Lemmel's syndrome secondary to common bile duct compression by an inflamed duodenal diverticulum","volume":"13","author":"Gao","year":"2021","journal-title":"Cureus"},{"key":"R10-20240830","first-page":"624","article-title":"Extracorporeal lithotripsy of intrahepatic stones with associated strictures of intrahepatic biliary ducts","volume":"30","author":"Muratori","year":"1998","journal-title":"Ital J Gastroenterol Hepatol"}],"container-title":["Journal of Medical Ultrasound"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jmu.jmu_39_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:27:54Z","timestamp":1787768874000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jmu.jmu_39_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,19]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jmu.jmu_39_22","relation":{},"ISSN":["0929-6441","2212-1552"],"issn-type":[{"value":"0929-6441","type":"print"},{"value":"2212-1552","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,19]]},"assertion":[{"value":"2022-05-04","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-10-21","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}