{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:01:22Z","timestamp":1787169682250,"version":"build-2736575974"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      We describe the case of a 35-year-old woman who comes to our institute with a palpable lump on her left breast. Clinically the mass was mobile, nontender and with no nipple discharge. Sonography revealed a circumscribed, oval-shaped, and hypoechoic mass, suggestive of a benign lesion. We performed an ultrasound-guided core needle biopsy that demonstrated multiple foci of high-grade (G3) ductal carcinoma\n                      <jats:italic toggle=\"yes\">in situ<\/jats:italic>\n                      arising on fibroadenoma (FA). Subsequently, the patient had surgical excision of the mass with a final diagnosis of triple-negative breast cancer arising on FA. After diagnosis, the patient performs a genetic test that detects the BRCA 1 gene mutation. A review of the literature demonstrated only two cases of triple-negative breast cancer on FA. In this report, we describe another such case.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jmu.jmu_83_21","type":"journal-article","created":{"date-parts":[[2023,3,21]],"date-time":"2023-03-21T09:31:22Z","timestamp":1679391082000},"page":"63-65","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Triple-negative Breast Cancer Arising in a Fibroadenoma in BRCA 1 Mutated Patient"],"prefix":"10.4103","volume":"31","author":[{"given":"Nicole","family":"Brunetti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"Valente","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Pitto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Calabrese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-13-20240830","first-page":"372","article-title":"Beware of breast fibroadenomas in middle-aged women","volume":"28","author":"Desch\u00eanes","year":"1985","journal-title":"Can J Surg"},{"key":"R2-13-20240830","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1007\/BF02471669","article-title":"Carcinoma arising in fibroadenoma of the breast \u2013 A case report and review of the literature","volume":"19","author":"Fukuda","year":"1989","journal-title":"Jpn J Surg"},{"key":"R3-13-20240830","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1093\/ajcp\/95.5.614","article-title":"Carcinoma arising within fibroadenomas of the breast. A clinicopathologic study of 105 patients","volume":"95","author":"Diaz","year":"1991","journal-title":"Am J Clin Pathol"},{"key":"R4-13-20240830","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1186\/1477-7819-12-335","article-title":"Breast cancer arising within fibroadenoma: Collective analysis of case reports in the literature and hints on treatment policy","volume":"12","author":"Wu","year":"2014","journal-title":"World J Surg Oncol"},{"key":"R5-13-20240830","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.ijscr.2020.02.059","article-title":"Locally advanced triple negative breast cancer arising from fibroadenoma with complete response to neoadjuvant chemotherapy: A case report","volume":"68","author":"Shiino","year":"2020","journal-title":"Int J Surg Case Rep"},{"key":"R6-13-20240830","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15436\/2377-0902.14.006","article-title":"Metastatic carcinoma arising from fibroadenoma of the breast","volume":"1","author":"Buteau","year":"2014","journal-title":"Int J Cancer Oncol"},{"key":"R7-13-20240830","first-page":"19","article-title":"Carcinoma in a fibroadenoma","volume":"41","author":"Sarela","year":"1995","journal-title":"J Postgrad Med"},{"key":"R8-13-20240830","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1148\/radiology.176.2.2164233","article-title":"Carcinoma within fibroadenomas: Mammographic features","volume":"176","author":"Baker","year":"1990","journal-title":"Radiology"},{"key":"R9-13-20240830","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1634\/theoncologist.2013-0380","article-title":"Triple-negative breast cancers: Associations between imaging and pathological findings for triple-negative tumors compared with hormone receptor-positive\/human epidermal growth factor receptor-2-negative breast cancers","volume":"18","author":"Boisserie-Lacroix","year":"2013","journal-title":"Oncologist"},{"key":"R10-13-20240830","first-page":"505","article-title":"Common breast problems","volume":"99","author":"Salzman","year":"2019","journal-title":"Am Fam Physician"}],"container-title":["Journal of Medical Ultrasound"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jmu.jmu_83_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:10:03Z","timestamp":1787166603000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jmu.jmu_83_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/jmu.jmu_83_21","relation":{},"ISSN":["0929-6441"],"issn-type":[{"value":"0929-6441","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1]]}}}