{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T10:34:06Z","timestamp":1766486046915},"reference-count":13,"publisher":"Scientific Scholar","issue":"S 01","license":[{"start":{"date-parts":[[2019,9,3]],"date-time":"2019-09-03T00:00:00Z","timestamp":1567468800000},"content-version":"vor","delay-in-days":763,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neurosciences in Rural Practice"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>\n          Background: Dementias are fairly slowly progressive degenerative diseases of brain for which treatment options are very less and carry a lot of burden on family and society. A small percentage of them are rapidly progressive and mostly carry a different course outcome. However, there are no definite criteria other than the time line for these patients. Aims: The aim of this was to identify and categorize the causes and course of rapidly progressive dementias seen in our center. Settings and Design: Patients who presented with rapid deterioration of cognitive functions within weeks to 1 year between 2011 and December 2016 were evaluated. Patients and Methods: All patients underwent all mandatory tests for dementia including brain imaging. Complete vasculitis workup, autoimmune encephalitis profile including Voltage Gated Potassium Channel, N-methyl-D-aspartic acid receptor, glutamic acid-decarboxylase, thyroid-peroxidase antibody, cerebrospinal fluid, and other special tests such as duodenal biopsy and paraneoplastic workup were done based on clinical indications. Results and Conclusions: Out of 144 patients 42 had immune-mediated encephalopathy, 18 had Creutzfeldt-Jakob disease, 3 had Vitamin B12 deficiency, 63 had infection with neurocysticercosis, 7 had tuberculosis, 2 had HIV, 1 had herpes simplex encephalitis, 1 had neurosyphilis, 1 Whipples disease, 1 had Subacute Sclerosing Panencephalitis, 1 had Mass lesion, 3 had Frontotemporal dementia, and 3 had small vessel disease. Good majority of these patients have infective and immune-mediated causes and less number belong to degenerative group. Therefore, caution is needed to look for treatable cause as it carries a different treatment options and outcome.<\/jats:p>","DOI":"10.4103\/jnrp.jnrp_100_17","type":"journal-article","created":{"date-parts":[[2017,8,23]],"date-time":"2017-08-23T12:38:08Z","timestamp":1503491888000},"page":"S66-S71","source":"Crossref","is-referenced-by-count":6,"special_numbering":"S","title":["Syndromes of Rapidly Progressive Cognitive Decline-Our Experience"],"prefix":"10.25259","volume":"08","author":[{"given":"Sadanandavalli Retnaswami","family":"Chandra","sequence":"additional","affiliation":[{"name":"Department of Neurology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lakshminarayanapuram Gopal","family":"Viswanathan","sequence":"additional","affiliation":[{"name":"Department of Neurology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anupama Ramakanth","family":"Pai","sequence":"additional","affiliation":[{"name":"Department of Neuromicrobiology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rahul","family":"Wahatule","sequence":"additional","affiliation":[{"name":"Department of Neurology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suvarna","family":"Alladi","sequence":"additional","affiliation":[{"name":"Department of Neurology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2019,9,3]]},"reference":[{"key":"key-10.4103\/0976-3147.213596-1","first-page":"97","volume-title":"Rapidly progressive dementia","author":"Geschwind","year":"2008","journal-title":"Ann Neurol"},{"key":"key-10.4103\/0976-3147.213596-2","first-page":"438","volume-title":"Creutzfeldt-Jakob disease phenotype and course: Our experience from a tertiary center","author":"Chandra","year":"2016","journal-title":"Indian J Psychol Med","ISSN":"http:\/\/id.crossref.org\/issn\/0253-7176","issn-type":"print"},{"key":"key-10.4103\/0976-3147.213596-3","first-page":"719","volume-title":"Frontotemporal dementia progresses to death faster than Alzheimer disease","author":"Roberson","year":"2005","journal-title":"Neurology"},{"key":"key-10.4103\/0976-3147.213596-4","unstructured":"Becker JT, Farbman ES, Hamilton RL, Lopez OL. Dementia with Lewy bodies. Contemporary Neurobehavioral Syndromes. Joachim, Morris: Selkoe; 2011. p. 111-29."},{"key":"key-10.4103\/0976-3147.213596-5","first-page":"298","volume-title":"Differential diagnosis of 201 possible Creutzfeldt-Jakob disease patients","author":"Van","year":"2004","journal-title":"J Neurol"},{"key":"key-10.4103\/0976-3147.213596-6","first-page":"175","volume-title":"Whipple's disease: A review of 19 patients from one hospital and a review of the literature since 1950","author":"Maizel","year":"1970","journal-title":"Medicine (Baltimore)"},{"key":"key-10.4103\/0976-3147.213596-7","first-page":"783","volume-title":"Rapidly progressive dementia","author":"Geschwind","year":"2007","journal-title":"Neurol Clin"},{"key":"key-10.4103\/0976-3147.213596-8","doi-asserted-by":"crossref","unstructured":"Mastrianni JA, Roos RP. The prion diseases. In: Seminars in Neurology. Vol. 20. New York, USA: Copyright \u00a9 2000 by Thieme Medical Publishers, Inc.; 2000. p. 337-52.","DOI":"10.1055\/s-2000-9396"},{"key":"key-10.4103\/0976-3147.213596-9","unstructured":"Brown P. Guidelines for high risk autopsy cases: Special precautions for Creutzfeldt-Jakob disease. Autopsy Performance and Reporting. Northfield, Illinois: College of American Pathologists; 1990. p. 68-74."},{"key":"key-10.4103\/0976-3147.213596-10","first-page":"177","volume-title":", Tsang VC, Nash TE, Takayanagui OM, et al. Proposed diagnostic criteria for neurocysticercosis","author":"Del","year":"2001","journal-title":"Neurology"},{"key":"key-10.4103\/0976-3147.213596-11","first-page":"142","volume-title":"Cognitive dysfunction and its determinants in patients with neurocysticercosis","author":"Varghese","year":"2016","journal-title":"Indian J Psychol Med","ISSN":"http:\/\/id.crossref.org\/issn\/0253-7176","issn-type":"print"},{"key":"key-10.4103\/0976-3147.213596-12","first-page":"413","volume-title":"Catatonia in children following systemic illness","author":"Chandra","year":"2015","journal-title":"Indian J Psychol Med","ISSN":"http:\/\/id.crossref.org\/issn\/0253-7176","issn-type":"print"},{"key":"key-10.4103\/0976-3147.213596-13","first-page":"536","volume-title":"Elevated antimeasles antibody titre: An association in autoimmune encephalitis","author":"Chandra","year":"2015","journal-title":"J Neurosci Rural Pract","ISSN":"http:\/\/id.crossref.org\/issn\/0976-3147","issn-type":"print"}],"container-title":["Journal of Neurosciences in Rural Practice"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.4103\/jnrp.jnrp_100_17.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,5]],"date-time":"2023-08-05T04:17:52Z","timestamp":1691209072000},"score":1,"resource":{"primary":{"URL":"https:\/\/ruralneuropractice.com\/syndromes-of-rapidly-progressive-cognitive-decline-our-experience\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8]]},"references-count":13,"journal-issue":{"issue":"S 01","published-online":{"date-parts":[[2019,9,3]]},"published-print":{"date-parts":[[2017,8]]}},"URL":"https:\/\/doi.org\/10.4103\/jnrp.jnrp_100_17","relation":{},"ISSN":["0976-3147","0976-3155"],"issn-type":[{"value":"0976-3147","type":"print"},{"value":"0976-3155","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8]]}}}