{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T13:30:42Z","timestamp":1781703042956,"version":"3.54.5"},"reference-count":45,"publisher":"Scientific Scholar","issue":"02","license":[{"start":{"date-parts":[[2019,9,4]],"date-time":"2019-09-04T00:00:00Z","timestamp":1567555200000},"content-version":"vor","delay-in-days":886,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neurosciences in Rural Practice"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>\n          Background: Changes in platelet indices have been reported in patients with panic disorder (PD). However, previous study findings are contradictory and inconclusive. The aim of this study was to evaluate and compare the platelet indices in patients with PD. Materials and Methods: Patients with PD (n = 123) and healthy controls (n = 133) were enrolled in this case control study. The platelet indices (mean platelet volume [MPV] and platelet distribution width [PDW]) along with red blood cell (RBC) indices (RBC count and red cell distribution width [RDW]) were compared between the two groups using the unpaired t-test. Results: Patients with PD had lower MPV (7.53 \u00b1 0.93 fL vs. 8.91 \u00b1 1.24 fL, P &lt; 0.0001), higher PDW (16.96 \u00b1 0.85 fL vs. 14.71 \u00b1 2.07 fL, P &lt; 0.0001), and higher platelet count (274.2 \u00b1 80.66 \u00d7 109 L\u22121 vs. 243.1 \u00b1 93.89 \u00d7 109 L\u22121, P &lt; 0.005) than the healthy controls. Furthermore, there were significant differences between patients with PD and healthy controls in terms of their RBC count (4.32 \u00b1 0.56 \u00d7 1012 L\u22121 vs. 4.08 \u00b1 0.80 \u00d7 1012 L\u22121, P = 0.007) and RDW (16.48 \u00b1 2.26 fL vs. 15.01 \u00b1 2.25 fL, P &lt; 0.0001). Conclusion: Patients with PD have increased PDW and RDW. The platelet and RBC indices may prove to be useful etiological and prognostic markers in patients with PD.<\/jats:p>","DOI":"10.4103\/jnrp.jnrp_445_16","type":"journal-article","created":{"date-parts":[[2017,4,5]],"date-time":"2017-04-05T13:45:47Z","timestamp":1491399947000},"page":"174-178","source":"Crossref","is-referenced-by-count":26,"title":["Mean Platelet Volume and Platelet Distribution Width Level in Patients with Panic Disorder"],"prefix":"10.25259","volume":"08","author":[{"given":"Ramdas Sarjerao","family":"Ransing","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, B K L Walawalkar Rural Medical College, Ratnagiri, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bharat","family":"Patil","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Maharishi Markandeshwar Medical College and Hospital, Kumarhatti-Solan, Himachal Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omityah","family":"Grigo","sequence":"additional","affiliation":[{"name":"Department of Pathology, Mahatma Gandhi Institute of Medical Sciences, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2019,9,4]]},"reference":[{"key":"key-10.4103\/0976-3147.203838-1","first-page":"159","volume-title":"Treatment-resistant panic disorder: A systematic review","author":"Freire","year":"2016","journal-title":"Expert Opin Pharmacother"},{"key":"key-10.4103\/0976-3147.203838-2","unstructured":"American Psychiatric Association. 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