{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,26]],"date-time":"2024-07-26T08:26:36Z","timestamp":1721982396048},"reference-count":0,"publisher":"Scientific Scholar","issue":"03","license":[{"start":{"date-parts":[[2019,9,2]],"date-time":"2019-09-02T00:00:00Z","timestamp":1567382400000},"content-version":"vor","delay-in-days":428,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neurosciences in Rural Practice"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>\n          Aim: To prospectively study the clinical profile, angiographic features, and functional outcomes, in consecutive cases of extracranial dissection seen at two tertiary stroke care centers in South India. Materials and Methods: In this observational study, spanning 4 years (December 12\u2013December 16), a total of 442 patients presented with an acute ischemic stroke\/transient ischemic attack (TIA) at our study centers. 14\/546 (3.2%) of these patients had magnetic resonance angiography (MRA)\/computed tomography angiography (CTA) evidence of extracranial dissections. All cases underwent detailed clinical evaluation on arrival, and data were recorded on a predesigned stroke pro forma. Contrast MRA was done on arrival in all cases as part of a standard stroke protocol, and CTA was done only if MRA was inconclusive. The pattern of the vessel involved and morphology of vessel dissection was analyzed as per a standard radiology protocol. All the cases were managed with short-term anticoagulation using low-molecular-weight heparin followed by oral anticoagulants for 3\u20136 months. All cases were followed up for 1\u20132 years and the functional outcomes were recorded using the modified Rankin Scale (mRS). Results: There were 11 males and 3 females in the study, and the mean age was 45.1 years (range = 27\u201365 years). Focal neurological symptoms occurred in all these patients (10 patients had a stroke, and 4 had TIA). Nearly 64.2% of these (9\/14) were stroke in young (age &lt;45 years). The internal carotid artery was the most common vessel involved in 85.7% (12\/14) cases. Of the ten patients with completed stroke, a good functional outcome (mRS 1\u20132) was seen in 8\/10 (80%). Digital subtraction angiography and revascularization procedures were needed only in a minority of cases 3\/14 (21%).\\ Conclusion: This hospital-based study highlights the importance of suspecting arterial dissections in young strokes of unexplained etiology, and offering optimum anticoagulant therapy in the acute phase, to achieve good long-term outcomes.<\/jats:p>","DOI":"10.4103\/jnrp.jnrp_540_17","type":"journal-article","created":{"date-parts":[[2018,7,5]],"date-time":"2018-07-05T07:40:39Z","timestamp":1530776439000},"page":"344-349","source":"Crossref","is-referenced-by-count":2,"title":["A Study on the Clinical and Angiographic Spectrum of Spontaneous Extracranial Dissections in the Cerebral Vasculature"],"prefix":"10.25259","volume":"09","author":[{"given":"Ravi K.","family":"Anadure","sequence":"additional","affiliation":[{"name":"Department of Medicine and Command Hospital Air Force, Bengaluru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aneesh","family":"Mohimen","sequence":"additional","affiliation":[{"name":"Department of Radiology, Command Hospital Air Force, Bengaluru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajeev","family":"Saxena","sequence":"additional","affiliation":[{"name":"Department of Radiology, Command Hospital Air Force, Bengaluru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajeev","family":"Sivasankar","sequence":"additional","affiliation":[{"name":"Department of Radiology, INHS Asvini, Mumbai, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2019,9,2]]},"container-title":["Journal of Neurosciences in Rural Practice"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.4103\/jnrp.jnrp_540_17.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,5]],"date-time":"2023-08-05T04:17:13Z","timestamp":1691209033000},"score":1,"resource":{"primary":{"URL":"https:\/\/ruralneuropractice.com\/a-study-on-the-clinical-and-angiographic-spectrum-of-spontaneous-extracranial-dissections-in-the-cerebral-vasculature\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7]]},"references-count":0,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2019,9,2]]},"published-print":{"date-parts":[[2018,7]]}},"URL":"https:\/\/doi.org\/10.4103\/jnrp.jnrp_540_17","relation":{},"ISSN":["0976-3147","0976-3155"],"issn-type":[{"value":"0976-3147","type":"print"},{"value":"0976-3155","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7]]}}}