{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T19:40:31Z","timestamp":1786736431870,"version":"build-2736575974"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Anaesthesiol Clin Pharmacol"],"published-print":{"date-parts":[[2019]]},"DOI":"10.4103\/joacp.joacp_196_17","type":"journal-article","created":{"date-parts":[[2019,6,28]],"date-time":"2019-06-28T05:31:36Z","timestamp":1561699896000},"page":"182","source":"Crossref","is-referenced-by-count":14,"title":["A randomized study to compare palonosetron with ondansetron for prevention of postoperative nausea and vomiting following middle ear surgeries"],"prefix":"10.4103","volume":"35","author":[{"given":"Shubhangi","family":"Sharma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sangeeta","family":"Khanna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jyotirmoy","family":"Das","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yatin","family":"Mehta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"KumudKumar","family":"Handa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"key-10.4103\/0970-9185.261283-1","first-page":"162","volume-title":"Postoperative nausea and vomiting.Its etiology, treatment, and prevention","author":"Watcha","year":"1992","journal-title":"Anesthesiology"},{"key":"key-10.4103\/0970-9185.261283-2","first-page":"693","volume-title":"A simplified risk score for predicting postoperative nausea and vomiting: Conclusions from cross-validations between two centers","author":"Apfel","year":"1999","journal-title":"Anesthesiology"},{"key":"key-10.4103\/0970-9185.261283-3","first-page":"1441","volume-title":"Aphase III, double-blind, randomized trial of palonosetron compared with ondansetron in preventing chemotherapy-induced nausea and vomiting following highly emetogenic chemotherapy","author":"Aapro","year":"2006","journal-title":"Ann Oncol"},{"key":"key-10.4103\/0970-9185.261283-4","first-page":"439","volume-title":"et al. Arandomized, double-blind study to evaluate the efficacy and safety of three different doses of palonosetron versus placebo in preventing postoperative nausea and vomiting over a 72-hour period","author":"Kovac","year":"2008","journal-title":"Anesth Analg"},{"key":"key-10.4103\/0970-9185.261283-5","first-page":"445","volume-title":"et al. Arandomized, double-blind study to evaluate the efficacy and safety of three different doses of palonosetron versus placebo for preventing postoperative nausea and vomiting","author":"Candiotti","year":"2008","journal-title":"Anesth Analg"},{"key":"key-10.4103\/0970-9185.261283-6","first-page":"2257","volume-title":"Palonosetron: In the prevention of nausea and vomiting","author":"Yang","year":"2009","journal-title":"Drugs"},{"key":"key-10.4103\/0970-9185.261283-7","doi-asserted-by":"crossref","unstructured":"Stoltz R, Cyong JC, Shah A, Parisi S. Pharmacokinetic and safety evaluation of palonosetron, a 5-hydroxytryptamine-3 receptor antagonist, in U.S. And Japanese healthy subjects. J Clin Pharmacol 2004;44:520-31.","DOI":"10.1177\/0091270004264641"},{"key":"key-10.4103\/0970-9185.261283-8","first-page":"122","volume-title":"Comparison of palonosetron with ondansetron in prevention of postoperative nausea and vomiting in patients receiving intravenous patient-controlled analgesia after gynecological laparoscopic surgery","author":"Kim","year":"2013","journal-title":"Korean J Anesthesiol"},{"key":"key-10.4103\/0970-9185.261283-9","first-page":"1277","volume-title":"Efficacy, dose-response, and safety of ondansetron in prevention of postoperative nausea and vomiting: A quantitative systematic review of randomized placebo-controlled trials","author":"Tram\u00e8r","year":"1997","journal-title":"Anesthesiology"},{"key":"key-10.4103\/0970-9185.261283-10","first-page":"95","volume-title":"Ondansetron clinical pharmacokinetics","author":"Roila","year":"1995","journal-title":"Clin Pharmacokinet"},{"key":"key-10.4103\/0970-9185.261283-11","first-page":"24","volume-title":"Evaluation of antiemetic effect of intravenous palonosetron versus intravenous ondansetron in laparoscopic cholecystectomy: A randomized controlled trial","author":"Laha","year":"2013","journal-title":"Indian J Pharmacol","ISSN":"https:\/\/id.crossref.org\/issn\/0253-7613","issn-type":"print"},{"key":"key-10.4103\/0970-9185.261283-12","first-page":"7","volume-title":"The postoperative interview: Assessing risk factors for nausea and vomiting","author":"Cohen","year":"1994","journal-title":"Anesth Analg"},{"key":"key-10.4103\/0970-9185.261283-13","first-page":"60S","volume-title":"The role of 5-HT in postoperative nausea and vomiting","author":"Bunce","year":"1992","journal-title":"Br J Anaesth"},{"key":"key-10.4103\/0970-9185.261283-14","first-page":"62","volume-title":"Consensus guidelines for managing postoperative nausea and vomiting","author":"Gan","year":"2003","journal-title":"Anesth Analg"},{"key":"key-10.4103\/0970-9185.261283-15","first-page":"469","volume-title":"Palonosetron exhibits unique molecular interactions with the 5-HT3 receptor","author":"Rojas","year":"2008","journal-title":"Anesth Analg"},{"key":"key-10.4103\/0970-9185.261283-16","first-page":"417","volume-title":"Anti-emetic effect of ondansetron and palonosetron in thyroidectomy: A prospective, randomized, double-blind study","author":"Moon","year":"2012","journal-title":"Br J Anaesth"},{"key":"key-10.4103\/0970-9185.261283-17","first-page":"1486","volume-title":"Comparision of palonosetron with ondansetron for prevention of nausea and vomiting during postoperative period in patients undergoing ENT surgeries","author":"Rao","year":"2017","journal-title":"Int J Contemp Med Res"},{"key":"key-10.4103\/0970-9185.261283-18","first-page":"156","volume-title":"Palonosetron in preventing postoperative nausea and vomiting in middle ear surgery: A randomized-controlled study","author":"Elahl","year":"2013","journal-title":"Egypt J Otolaryngol","ISSN":"https:\/\/id.crossref.org\/issn\/1012-5574","issn-type":"print"},{"key":"key-10.4103\/0970-9185.261283-19","first-page":"327","volume-title":"Comparison of palanosetron, granisetron and ondansetron as anti-emetics for prevention of postoperative nausea and vomiting in patients undergoing middle ear surgery","author":"Basu","year":"2011","journal-title":"J Indian Med Assoc"},{"key":"key-10.4103\/0970-9185.261283-20","first-page":"331","volume-title":"The effect of timing of ondansetron administration in outpatients undergoing otolaryngologic surgery","author":"Sun","year":"1997","journal-title":"Anesth Analg"},{"key":"key-10.4103\/0970-9185.261283-21","first-page":"1407","volume-title":"5-hydroxytryptamine3 receptor antagonists and cardiac side effects","author":"Brygger","year":"2014","journal-title":"Expert Opin Drug Saf"},{"key":"key-10.4103\/0970-9185.261283-22","first-page":"460","volume-title":"Effect of palonosetron on the QTc interval in patients undergoing sevoflurane anaesthesia","author":"Kim","year":"2014","journal-title":"Br J Anaesth"}],"container-title":["Journal of Anaesthesiology Clinical Pharmacology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T18:41:43Z","timestamp":1786732903000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/joacp.JOACP_196_17"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019]]}},"alternative-id":["261283"],"URL":"https:\/\/doi.org\/10.4103\/joacp.joacp_196_17","relation":{},"ISSN":["0970-9185"],"issn-type":[{"value":"0970-9185","type":"print"}],"subject":[],"published":{"date-parts":[[2019]]}}}