{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:32:01Z","timestamp":1787761921528,"version":"build-2784847793"},"reference-count":26,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,7]]},"abstract":"Abstract<\/jats:title>\n \n Background and Aims:<\/jats:title>\n \n Doppler waveform analysis of carotid artery has been found to predict fluid responsiveness in patients undergoing elective surgeries. We evaluated the role of carotid artery corrected flow time (FTc) and respiratory variation of blood flow peak velocity (\u00f0V\n peak<\/jats:sub>\n ) in predicting post induction hypotension in patients undergoing emergency laparotomy for peritonitis.\n <\/jats:p>\n <\/jats:sec>\n \n Material and Methods:<\/jats:title>\n \n Adult patients (\n n<\/jats:italic>\n = 60) with perforation peritonitis undergoing emergency laparotomy under general anesthesia (GA) were recruited in this prospective, observational study. Carotid ultrasonography was performed pre-induction, to determine FTc and \u00f0V\n peak<\/jats:sub>\n . Post-induction hemodynamic parameters were recorded for 5 minutes. Spearman\u2019s rank correlation coefficient was used to determine the relationship between hypotension and carotid artery measurements.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n Post-induction hypotension occurred in 48.3% of patients. The carotid artery FTc was significantly lower (\n P<\/jats:italic>\n = 0.008) in patients who developed post-induction hypotension, but \u00f0V\n peak<\/jats:sub>\n was statistically similar (\n P<\/jats:italic>\n = 0.62) in both groups. Spearman\u2019s rank correlation coefficient revealed a statistically significant correlation between FTc and systolic blood pressure (SBP) change at one-minute post induction (\n r2<\/jats:italic>\n =<\/jats:italic>\n \u22120.29,\n P<\/jats:italic>\n = 0.03); however statistical significance were not achieved at 2 minutes and 3 minutes (\n P<\/jats:italic>\n = 0.05 at both time points). Carotid artery FTc had an area under the receiver operating characteristic (AUROC) curve (95% CI) of 0.70 (0.57\u20130.84) to predict post-induction hypotension and best cutoff value of 344.8 ms with a sensitivity and specificity of 61% and 79%, respectively. Carotid artery \u00f0V\n peak<\/jats:sub>\n had an AUROC curve (95% CI) of 0.54 (0.39\u20130.69) to predict post-induction hypotension and best cutoff value of 7.9% with a sensitivity and specificity of 62% and 55%, respectively.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n \n Carotid artery FTc and \u00f0V\n peak<\/jats:sub>\n are not reasonable predictors of hypotension in patients undergoing emergency laparotomy for perforation peritonitis.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/joacp.joacp_372_21","type":"journal-article","created":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T22:00:15Z","timestamp":1683842415000},"page":"444-450","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Carotid artery corrected flow time and respiratory variation of blood flow peak velocity for prediction of hypotension after induction of general anesthesia in adult patients undergoing emergency laparotomy for peritonitis: A prospective, observational study"],"prefix":"10.4103","volume":"39","author":[{"given":"Apala R.","family":"Chowdhury","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology, Pain Medicine and Critical Care, All India Institute of Medical Sciences, New Delhi, India"},{"name":"Department of Anaesthesia and Pain Medicine, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruma","family":"Thakuria","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Pain Medicine and Critical Care, All India Institute of Medical Sciences, New Delhi, India"},{"name":"Department of Anaesthesia and Critical Care, Max Hospital, Dehradun, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Souvik","family":"Maitra","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Pain Medicine and Critical Care, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sayan","family":"Nath","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Pain Medicine and Critical Care, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dalim K.","family":"Baidya","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Pain Medicine and Critical Care, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajeshwari","family":"Subramanium","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Pain Medicine and Critical Care, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahul K.","family":"Anand","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Pain Medicine and Critical Care, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Choro A.","family":"Kayina","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Pain Medicine and Critical Care, All India Institute of Medical Sciences, New Delhi, India"},{"name":"Department of Anaesthesia and Intensive Care, Post Graduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,5,5]]},"reference":[{"key":"R1-20240828","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1213\/01.ANE.0000175214.38450.91","article-title":"Predictors of hypotension after induction of general anesthesia","volume":"101","author":"Reich","year":"2005","journal-title":"Anesth Analg"},{"key":"R2-20240828","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1007\/s00540-018-2532-6","article-title":"Hypotension after induction of general anesthesia:Occurrence, risk factors, and therapy. 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