{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,8]],"date-time":"2026-11-08T00:42:29Z","timestamp":1794098549181,"version":"4.8.0"},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","license":[{"start":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T00:00:00Z","timestamp":1779148800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims:<\/jats:title>\n                    <jats:p>Central venous cannulation in neonates and infants is technically challenging due to small vessel size and vein collapsibility. Although ultrasound-guided (USG) internal jugular vein (IJV) cannulation is commonly used, supraclavicular in-plane brachiocephalic vein (BCV) cannulation has emerged as a newer approach with several advantages because of its straighter course, larger diameter, and reduced collapsibility. The aim of this study was to compare the USG-guided in-plane IJV vs supraclavicular in-plane BCV cannulation in neonates and infants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods:<\/jats:title>\n                    <jats:p>\n                      This prospective randomized controlled trial (RCT) was commenced after obtaining institutional ethical clearance (EC\/OA-67\/2022) and registered with CTRI (REF\/2023\/08\/071780). A total of 80 neonates and infants satisfying the eligibility criteria were included for this study, with 40 each being randomly allotted either to group A (USG in-plane right IJV cannulation) or group B (USG supraclavicular in-plane left BCV cannulation). Written informed parental consent was obtained for all the participants. The primary outcome was 1\n                      <jats:sup>st<\/jats:sup>\n                      attempt success rate. Secondary outcomes included cannulation time, number of attempts, overall success rate, and complications.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      First-attempt success rate was higher in BCV than in the IJV group (95% vs 77.50%,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      value = 0.02) (95% CI: 3.2\u201331.8). Cannulation time was less in the BCV group (50.70 \u00b1 58.51 secs vs 86.63 \u00b1 60.19 secs:\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      value &lt; 0. 008) (95% CI: \u221262.5 to \u22129.3) as compared to the IJV group. Overall success rate was slightly higher in the BCV group (100% vs 97.50%,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      value = 0.31) (95% CI: \u22122.4% to 7.4%) along with a reduced number of attempts (1.08 \u00b1 0.35 vs 1.30 \u00b1 0.65,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      value = 0.057) (95% CI: \u22120.45 to 0.01). No immediate or late complications (within 48 hours) were observed in both the groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>USG in-plane left BCV cannulation improved first-attempt success rate and cannulation time as compared to in-plane right IJV cannulation with a reduced number of attempts. Brachiocephalic central venous cannulation may have advantages over IJV access, especially in critically ill neonates and infants, making it a feasible and safe alternative to IJV.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/joacp.joacp_492_25","type":"journal-article","created":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T09:00:09Z","timestamp":1779181209000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Comparison of ultrasound-guided brachiocephalic and internal jugular vein cannulation in neonates and infants: A prospective randomized controlled trial"],"prefix":"10.4103","author":[{"given":"Uditi","family":"Parmar","sequence":"first","affiliation":[{"name":"Pediatric Anaesthesiology, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, 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