{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:32:27Z","timestamp":1787761947287,"version":"build-2784847793"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims:<\/jats:title>\n                    <jats:p>Surgical procedure commonly performed in the advanced pediatric age group includes urogenital surgery, adenotonsillectomy, etc., Aim: The aim of this study is to determine the effect of single-dose gabapentin 15 mg\/kg on acute pain in the immediate postoperative period in patients aged 8\u201314 years undergoing surgeries under general anesthesia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods:<\/jats:title>\n                    <jats:p>After the approval from the institutional ethical committee, 60 American Society of Anesthesiologists (ASA) I and II patients aged 8\u201314 years undergoing urogenital surgeries (orchidopexy\/urethroplasty) under general anesthesia were included in this study. The patients were assigned into one of the two treatment groups. Patients in group I received oral gabapentin 15 mg\/kg dissolved in 5 mL of honey 2 h before surgery, while patients in group II received 5 mL honey orally 2 h before surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 60 patients participated. Patients in group I had lower consumption of fentanyl perioperatively (intraoperatively: 1.36 \u00b1 0.70 mcg\/kg; postoperatively: 2.36 \u00b1 0.795 mcg\/kg) than group II (intraoperatively: 1.8 \u00b1 0.6 mcg\/kg; postoperatively: 2.9 \u00b1 0.47 mcg\/kg). The differences in the two groups were significant. The time to first rescue analgesia was greater in group I (3.03 \u00b1 0.60 h) than in group II (2.26 \u00b1 0.57 h). There was an increase in sedation score in the treatment group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Our clinical study demonstrates that a 15 mg\/kg single preemptive oral dose of gabapentin might reduce the requirement of analgesics perioperatively in pediatric urogenital surgery but might also be associated with undesirable effects such as increased sedation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/joacp.joacp_503_21","type":"journal-article","created":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T07:00:09Z","timestamp":1684825209000},"page":"539-543","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Perioperative role of oral gabapentin as an analgesic in paediatric patients: A randomised controlled trial"],"prefix":"10.4103","volume":"39","author":[{"given":"Chandni","family":"Sinha","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology, All India Institute of Medical Sciences, Patna, Bihar, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amarjeet","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Trauma and Emergency, All India Institute of Medical Sciences, Patna, Bihar, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajeet","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, All India Institute of Medical Sciences, Patna, Bihar, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Poonam","family":"Kumari","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, All India Institute of Medical Sciences, Patna, Bihar, 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