{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T22:12:16Z","timestamp":1788473536368,"version":"build-2803163510"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Mesotheliomas are neoplasms of the serosal lining of the body cavities. Diagnosis requires a multimodal approach of clinical findings, cytology, and histopathology with immunohistochemistry (IHC). The published sensitivity of cytology for diagnosing mesothelioma ranges from 30% to 75%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim and Objectives:<\/jats:title>\n                    <jats:p>This study aimed to calculate the incidence of malignant mesothelioma (MM) at our institute and to study the cytological features of MM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>A retrospective study of pleural, peritoneal, and pericardial fluids submitted at our institute was done. The duration of the study was 8 years (2011\u20132019). Apart from examining Giemsa smears, a panel of immunocytochemical (ICC) and cell block immunohistochemical (IHC) markers was applied to achieve the diagnosis. These included calretinin, mesothelin, CK5\/6, Hector Battifora mesothelial cell antibody (HBME), WT1, MOC31, CK7 and CK20. Histopathological correlation was done wherever possible.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Result:<\/jats:title>\n                    <jats:p>In the present study, we compiled four cases of MM over 8 years diagnosed on serous effusion cytology and confirmed by immunocytochemistry (ICC)\/cell block immunohistochemistry (IHC)\/biopsy. This indicates a rare incidence of MM. The Cytological features of MM were studied.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The diagnosis of MM is difficult, especially cytologically. It was found to be a rare entity in the malignant cases diagnosed on effusion cytology.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/joc.joc_145_21","type":"journal-article","created":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T10:03:39Z","timestamp":1659089019000},"page":"105-109","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":7,"title":["Cytological Diagnosis of Malignant Mesothelioma"],"prefix":"10.4103","volume":"39","author":[{"given":"Sakshi","family":"Dahiya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meeta","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shyama","family":"Jain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bembem","family":"Khuraijam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naman","family":"Suroya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shramana","family":"Mandal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-3-20240905","doi-asserted-by":"crossref","first-page":"814","DOI":"10.2214\/AJR.07.3628","article-title":"Peritoneal mesotheliomas: Clinicopathologic features, CT findings, and differential diagnosis","volume":"191","author":"Park","year":"2008","journal-title":"Am J Roentgenol"},{"key":"R2-3-20240905","doi-asserted-by":"crossref","first-page":"150","DOI":"10.2298\/AOO0504150K","article-title":"Primary pericardial mesothelioma presenting as constrictive pericarditis","volume":"13","author":"Karadzic","year":"2005","journal-title":"Arc Oncol"},{"key":"R3-3-20240905","doi-asserted-by":"crossref","first-page":"82","DOI":"10.4103\/0019-5278.146897","article-title":"Global mesothelioma epidemic: Trend and features","volume":"18","author":"Bianchi","year":"2014","journal-title":"Indian J Occup Environ Med"},{"key":"R4-3-20240905","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1002\/jso.2930490313","article-title":"Primary pleural mesotheliomas in South India: A 25-year study","volume":"49","author":"Kini","year":"1992","journal-title":"J Surg Oncol"},{"key":"R5-3-20240905","first-page":"1208","article-title":"Malignant pleural mesothelioma","volume":"49","author":"Nadgouda","year":"2001","journal-title":"J Assoc Physicians India"},{"key":"R6-3-20240905","doi-asserted-by":"crossref","first-page":"31","DOI":"10.4103\/0970-2113.44137","article-title":"Malignant pleural mesothelioma without asbestos exposure with distant metastasis in a peripheral lymph node: A case report","volume":"25","author":"Kant","year":"2008","journal-title":"Lung India"},{"key":"R7-3-20240905","doi-asserted-by":"crossref","first-page":"e227882","DOI":"10.1136\/bcr-2018-227882","article-title":"A case from India of pleural malignant mesothelioma probably due to domestic and environmental asbestos exposure: A posthumous report","volume":"12","author":"Muralidhar","year":"2019","journal-title":"BMJ Case Rep"},{"key":"R8-3-20240905","doi-asserted-by":"crossref","first-page":"190","DOI":"10.4103\/ijc.IJC_584_17","article-title":"Malignant mesothelioma: A histomorphological and immunohistochemical study of 24 cases from a tertiary care hospital in Southern India","volume":"55","author":"Hui","year":"2018","journal-title":"Indian J Cancer"},{"key":"R9-3-20240905","doi-asserted-by":"crossref","first-page":"93","DOI":"10.4103\/ijoem.IJOEM_237_18","article-title":"Malignant mesothelioma - Report of two cases with different presentations","volume":"23","author":"Munot","year":"2019","journal-title":"Indian J Occup Environ Med"},{"key":"R10-3-20240905","doi-asserted-by":"crossref","first-page":"602","DOI":"10.4103\/0973-1482.106574","article-title":"Cytomorphological profile of neoplastic effusions: An audit of 10 years with emphasis on uncommonly encountered malignancies","volume":"8","author":"Gupta","year":"2012","journal-title":"J Can Res Ther"},{"key":"R11-3-20240905","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1136\/jclinpath-2012-201303","article-title":"Challenges and controversies in the diagnosis of mesothelioma: Part 1. Cytology-only diagnosis, biopsies, immunohistochemistry, discrimination between mesothelioma and reactive mesothelial hyperplasia, and biomarkers","volume":"66","author":"Henderson","year":"2013","journal-title":"J Clin Pathol"},{"key":"R12-3-20240905","doi-asserted-by":"crossref","first-page":"89","DOI":"10.5858\/arpa.2017-0124-RA","article-title":"Guidelines for pathologic diagnosis of malignant mesothelioma 2017 update of the consensus statement from the International Mesothelioma Interest Group","volume":"142","author":"Husain","year":"2018","journal-title":"Arch Pathol Lab Med"},{"key":"R13-3-20240905","doi-asserted-by":"crossref","first-page":"318","DOI":"10.5858\/arpa.2015-0240-SA","article-title":"New markers for separating benign from malignant mesothelial proliferations: Are we there yet?","volume":"140","author":"Churg","year":"2016","journal-title":"Arch Pathol Lab Med"},{"key":"R14-3-20240905","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.crad.2019.12.001","article-title":"The role of imaging in malignant pleural mesothelioma: An update after the 2018 BTS guidelines","volume":"75","author":"Sinha","year":"2020","journal-title":"Clin Radiol"}],"container-title":["Journal of Cytology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/joc.joc_145_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:07:44Z","timestamp":1787756864000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/joc.joc_145_21"}},"subtitle":["A Case Series"],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/joc.joc_145_21","relation":{},"ISSN":["0970-9371"],"issn-type":[{"value":"0970-9371","type":"print"}],"subject":[],"published":{"date-parts":[[2022,7]]}}}