{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:20:52Z","timestamp":1787772052419,"version":"build-2784847793"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["J Cytol"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Objectives:<\/jats:title>\n                    <jats:p>Papillary lesions of the breast represent a diverse group of neoplasms with varying biological behavior, ranging from benign to malignant. Accurate diagnosis is critical for appropriate clinical management. This study aims to analyze the cytopathological features of papillary breast lesions to improve diagnostic accuracy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>A retrospective study was performed on cases of papillary neoplasm of the breast diagnosed on cytology followed by histopathology during the study period, after procuring institutional ethical committee clearance. The clinical, pathologic, and follow-up details were retrieved from the hospital records and the pathology database and were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The study identified distinct benign and malignant papillary lesions, including intraductal papilloma, papillary ductal carcinoma\n                      <jats:italic toggle=\"yes\">in situ<\/jats:italic>\n                      , encapsulated papillary carcinoma, and solid papillary carcinoma. The mean age of the study participants was 51.15 years. Benign neoplasms showed cohesive clusters and a clear background on cytology, while cases with atypical or malignant features demonstrated loss of myoepithelial cells, non-cohesive clusters, and necrotic\/dirty background.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Papillary breast lesions encompass a wide spectrum of pathology, necessitating precise cytologic and histopathologic evaluation. The presence or absence of myoepithelial markers aids in differentiating benign from malignant lesions. Identification of cytologic features of benign and malignant neoplasms can improve diagnostic accuracy, enhance patient management, and ensure timely intervention for malignant cases.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/joc.joc_49_25","type":"journal-article","created":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T07:00:59Z","timestamp":1772089259000},"page":"31-38","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["A Comprehensive Cytomorphological Analysis of Papillary Neoplasms of the Breast"],"prefix":"10.4103","volume":"43","author":[{"given":"Vaanya","family":"Kaushik","sequence":"first","affiliation":[{"name":"Department of Pathology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shreya","family":"Garg","sequence":"additional","affiliation":[{"name":"Department of Pathology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chethana Babu K.","family":"Udupa","sequence":"additional","affiliation":[{"name":"Department of Pathology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Mathew","sequence":"additional","affiliation":[{"name":"Department of Pathology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ranjini","family":"Kudva","sequence":"additional","affiliation":[{"name":"Department of Pathology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brij Mohan Kumar","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Pathology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,2,26]]},"reference":[{"key":"CIT0001-20260226","first-page":"446","article-title":"Adequacy and accuracy of fine needle aspiration cytology of papillary lesions of the breast with its histopathological correlation: A two-year study from a tertiary care centre","volume":"4","author":"Dutta","year":"2017","journal-title":"Int J Contemp Med Res"},{"key":"CIT0002-20260226","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1002\/cncy.22412","article-title":"Papillary lesions of the breast: A systematic evaluation of cytologic parameters","volume":"129","author":"Jamidi","year":"2021","journal-title":"Cancer Cytopathol"},{"key":"CIT0004-20260226","first-page":"100","article-title":"Diagnostic challenges in papillary lesions of the breast","volume":"50","author":"Rakha","year":"2018","journal-title":"Pathology (Phila)"},{"key":"CIT0006-20260226","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1002\/cncr.11062","article-title":"Mammary lesions diagnosed as \u201cpapillary\u201d by aspiration biopsy: 70 cases with follow-up","volume":"99","author":"Simsir","year":"2003","journal-title":"Cancer"},{"key":"CIT0007-20260226","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1159\/000334391","article-title":"The accuracy of the \u2019triple test\u2019 in the diagnosis of papillary lesions of the breast","volume":"56","author":"Papeix","year":"2012","journal-title":"Acta Cytol"},{"key":"CIT0008-20260226","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1159\/000325674","article-title":"Papillary breast lesions diagnosed on cytology. 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