{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:07:36Z","timestamp":1787170056924,"version":"build-2736575974"},"reference-count":6,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:p>A 12-year-old boy presented with abdominal distention for 1 year. On examination, he had massive hepatomegaly. Facial swelling in the maxillary region, palpable left cervical lymph nodes, and a nasal twang to his voice were detected. Imaging showed multiple hypodense liver lesions, necrotic mediastinal and hilar lymph nodes, multiple lytic\u2013sclerotic skeletal lesions, and lesions in the nasopharynx and maxilla. Fine needle aspirate (FNA) from the cervical lymph node yielded blood. FNA from the liver showed singly dispersed and cohesive clusters of tumor cells, with interspersed neutrophils and tingible body macrophages. Cells had scant to moderate fragile cytoplasm, enlarged vesicular nuclei, and prominent nucleoli. Immunohistochemistry on cell block revealed positivity for cytokeratin and Epstein\u2013Barr virus (EBV)-Latent Membrane Protein-1 (LMP1). A diagnosis of metastatic nasopharyngeal carcinoma was made, and was confirmed on a subsequent biopsy from the femur.<\/jats:p>","DOI":"10.4103\/joc.joc_69_22","type":"journal-article","created":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T07:24:33Z","timestamp":1697441073000},"page":"211-213","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Liver Metastasis from Nasopharyngeal Carcinoma Diagnosed on Fine Needle Aspiration Cytology"],"prefix":"10.4103","volume":"40","author":[{"given":"Ria","family":"Mahendru","sequence":"first","affiliation":[{"name":"Department of Pathology, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aanchal","family":"Kakkar","sequence":"additional","affiliation":[{"name":"Department of Pathology, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manisha","family":"Jana","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachna","family":"Seth","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Pediatric Oncology Division, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,10,16]]},"reference":[{"key":"R1-20240905","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S1470-2045(03)00956-2","article-title":"Childhood nasopharyngeal carcinoma:From biology to treatment","volume":"4","author":"Ayan","year":"2003","journal-title":"Lancet Oncol"},{"key":"R2-20240905","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1002\/jso.2930330310","article-title":"Distant metastases of nasopharyngeal carcinoma:A study of 256 male patients","volume":"33","author":"Ahmad","year":"1986","journal-title":"J Surg Oncol"},{"key":"R3-20240905","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1002\/dc.20216","article-title":"Fine-needle aspiration cytology of metastatic nasopharyngeal carcinoma","volume":"32","author":"Viguer","year":"2005","journal-title":"Diagn Cytopathol"},{"key":"R4-20240905","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1002\/(SICI)1097-0339(199809)19:3<168::AID-DC2>3.0.CO;2-9","article-title":"Fine-needle aspiration cytology of metastatic nasopharyngeal carcinoma","volume":"19","author":"Jayaram","year":"1998","journal-title":"Diagn Cytopathol"},{"key":"R5-20240905","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1002\/dc.2840070603","article-title":"Metastatic nasopharyngeal carcinoma:Cytologic features of 18 cases","volume":"7","author":"Grenko","year":"1991","journal-title":"Diagn Cytopathol"},{"key":"R6-20240905","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1002\/dc.10218","article-title":"Fine-needle aspiration cytology of metastatic nasopharyngeal carcinoma in cervical lymph nodes:Comparison with metastatic squamous-cell carcinoma, and Hodgkin's and non-Hodgkin's lymphoma","volume":"28","author":"Kollur","year":"2003","journal-title":"Diagn Cytopathol"}],"container-title":["Journal of Cytology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/joc.joc_69_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:18:19Z","timestamp":1787167099000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/joc.joc_69_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":6,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/joc.joc_69_22","relation":{},"ISSN":["0970-9371","0974-5165"],"issn-type":[{"value":"0970-9371","type":"print"},{"value":"0974-5165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10]]},"assertion":[{"value":"2022-04-24","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-08-16","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}