{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:28:36Z","timestamp":1786649316573,"version":"build-2736575974"},"reference-count":46,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To investigate the longitudinal changes in choroidal thickness following photorefractive keratectomy (PRK) in young adult myopes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>The study population (age: 28 \u00b1 1 years) consisted of 14 myopic subjects who underwent PRK for myopia correction, and a control group of 13 myopic subjects who did not undergo PRK. Measures of choroidal thickness were obtained at baseline in the control group, and before PRK in the treatment group, and then following 1-week, 1-month, 3 and 6 months. Changes in choroidal thickness across different regions were analyzed over time and between groups using linear mixed models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The mean spherical equivalent refraction was \u22123.36 \u00b1 0.31 diopter (D) in the treatment and \u22122.58 \u00b1 0.30 D in the control group (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &gt; 0.05) at baseline. Longitudinal changes in choroidal thickness were significantly different between the two groups (group by time interaction,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). The mean wide-field choroidal thickness increased 1-week post-PRK in the treatment group (8 \u00b1 3 \u03bcm), with this change in choroidal thickness significantly greater than the change in the control group (\u22121 \u00b1 3 \u03bcm;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.04). However, changes in the mean wide-field choroidal thickness were not significantly different between the two groups in 1-, 3-and 6-month follow-up visits (all\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &gt; 0.05). The observed longitudinal changes were not different across the macular and extramacular regions (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &gt; 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Small magnitude thickening of the choroid was found to occur uniformly across the wide-field region within 1 week following myopic PRK. However, this change in choroidal thickness was transient and no longer observed within 6 months post-PRK.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/joco.joco_120_24","type":"journal-article","created":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T14:00:37Z","timestamp":1766152837000},"page":"221-227","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Transient Changes in Wide-Field Choroidal Thickness after Photorefractive Keratectomy for Myopia: A Case\u2013Control Study"],"prefix":"10.4103","volume":"37","author":[{"given":"Negareh","family":"Yazdani","sequence":"first","affiliation":[{"name":"Department of Optometry, School of Paramedical Sciences, Mashhad University of Medical Sciences, Mashhad, Iran"},{"name":"Refractive Errors Research Center, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hosein","family":"Hoseini-Yazdi","sequence":"additional","affiliation":[{"name":"Contact Lens and Visual Optics Laboratory, Centre for Vision and Eye Research, Optometry and Vision Science, Queensland University of Technology, Brisbane, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nasser","family":"Shoeibi","sequence":"additional","affiliation":[{"name":"Eye Research Center, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali Akbar","family":"Derakhshan","sequence":"additional","affiliation":[{"name":"Eye Research Center, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abbas","family":"Azimi Khorasani","sequence":"additional","affiliation":[{"name":"Department of Optometry, School of Paramedical Sciences, Mashhad University of Medical Sciences, Mashhad, Iran"},{"name":"Refractive Errors Research Center, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asieh","family":"Ehsaei","sequence":"additional","affiliation":[{"name":"Department of Optometry, School of Paramedical Sciences, Mashhad University of Medical Sciences, Mashhad, Iran"},{"name":"Refractive Errors Research Center, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,12,19]]},"reference":[{"key":"R1-20251222","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1016\/j.ophtha.2016.01.006","article-title":"Global prevalence of myopia and high myopia and temporal trends from 2000 through 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