{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:21:13Z","timestamp":1787775673146,"version":"build-2784847793"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To investigate the changes in the optical corneal densitometry as an objective method in assessing the corneal light back-scattering before and 1 year after the annular intracorneal inlay (AICI) implantation into the keratoconic corneas.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Changes in the optical corneal densitometry, visual acuity, refractive, and tomographical status were assessed before and 1 year after the AICI implantation into the corneas with different stages of keratoconus. Optical corneal densitometry was evaluated using the Pentacam-HR in 0\u20132, 2\u20136, 6\u201310, and 10\u201312 mm rings in the anterior 120 \u03bc, central layers, posterior 60 \u03bc and also the total value were measured for cornea in the Grey Scale Unit criterion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Totally, 34 patients with keratoconus were studied; the uncorrected and best corrected visual acuity were increased after the surgery (0.98 \u00b1 0.25 to 0.53 \u00b1 0.30 logMAR,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001 and 0.26 \u00b1 0.18 to 0.19 \u00b1 0.14,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.007 logMAR, respectively); the spherical equivalent was decreased from \u22124.45 \u00b1 2.25 to \u2212 2.06 \u00b1 2.01 D (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.004). AICI implantation led to an increase in the amount of optical corneal densitometry in 0\u20132 mm central, 2\u20136 mm central, 6\u201310 mm central, total central, 2\u20136 mm posterior, and 2\u20136 mm total rings (all,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05); however, a decrease was observed in 0\u20132 mm anterior ring (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.049). Results of statistical analysis showed that the total optical corneal densitometry, anterior total, and posterior total back-scattering did not change after the AICI implantation (all,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &gt; 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Our results revealed a significant improvement in the visual function, including refractive error and visual acuity following the AICI implantation. Changes in the optical corneal densitometry were different in distinct regions and layers however, the total amount did not change after the AICI implantation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/joco.joco_154_20","type":"journal-article","created":{"date-parts":[[2024,9,10]],"date-time":"2024-09-10T15:24:44Z","timestamp":1725981884000},"page":"23-30","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["Changes in the Optical Corneal Densitometry, Visual Acuity, and Refractive Error after the Annular Intracorneal Inlay 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