{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:32:34Z","timestamp":1787841154408,"version":"build-2784847793"},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To report a case of aniridic fibrosis syndrome (AFS) after Ahmed glaucoma valve (AGV) surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Case report.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Two years post-AGV surgery in both eyes, a 3-year-old aniridic female presented with grayish discoloration of the right eye for the past 3 months. A slit-lamp examination of the right eye revealed an aniridic, hypotonic eye with a totally edematous cornea. A tube of the AGV was in place with a mature cataract subluxed superiorly. In addition, a thick, whitish vascularized membrane originating from the rudimentary iris to the inferior part of the subluxed lens was observed. Ultrasound biomicroscopy investigation confirmed a thick fibrotic membrane originating from the iris root and extending to the posterior part of the cataractous lens. The intraocular pressure of the right and left eye was 0 and 11 mmHg, respectively. A B-scan of the right eye revealed an axial length of 21 mm, optic disc swelling, and shallow choroidal detachment in the anterior 2\/3 of the posterior segment without retinal detachment. With the diagnosis of AFS, a pars plana vitrectomy, lensectomy, and membranectomy under keratoprosthesis and penetrating keratoplasty were planned.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Aniridic patients may undergo multiple ocular surgeries during their lifetime. One of the rarest surgical complications in these patients is AFS. Early diagnosis can be possible with serial slit-lamp examination and ultrasonographic studies to detect the disease in the early stages and prompt intervention. Here, in our case, the parents declined any surgical intervention.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/joco.joco_155_24","type":"journal-article","created":{"date-parts":[[2025,9,18]],"date-time":"2025-09-18T22:02:59Z","timestamp":1758232979000},"page":"453-456","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Aniridic Fibrosis Syndrome in a Child with Ahmed Glaucoma Valve: Report of a Case and Review of the Literature"],"prefix":"10.4103","volume":"36","author":[{"given":"Mohammad","family":"Banifatemi","sequence":"first","affiliation":[{"name":"Eye Research Center, The Five Senses Health Institute, Moheb Kowsar Hospital, Iran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reza","family":"Razeghinejad","sequence":"additional","affiliation":[{"name":"Glaucoma Service, Wills Eye Hospital, Philadelphia, PA, 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