{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:24:45Z","timestamp":1787840685117,"version":"build-2784847793"},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,1]]},"abstract":"Abstract<\/jats:title>\n \n Purpose:<\/jats:title>\n To compare the corneal epithelial thickness along the flat and steep meridians of corneas with low and high toricity.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n This was a prospective observational comparative study on healthy subjects with normal corneas seeking preoperative evaluation for refractive surgery at a university-based hospital. Subjects with up to 2 diopters (D) of corneal with-the-rule astigmatism were defined as low corneal toricity (CT), whereas cylinder > two-dimensional was considered as high CT. The anterior segment optical coherence tomography was conducted to measure the epithelial thickness along the principle meridians of CT over a diameter of 9 mm. At the eye level, outcome variables (corneal and epithelial thicknesses in low- and high-astigmatism groups) were assessed using generalized estimating equation models.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n Included were 98 eyes (49 subjects): 46 eyes (23 subjects) with low CT and 52 eyes (26 subjects) with high CT. Two groups were similar with respect to the age (\n P<\/jats:italic>\n = 0.82), sex (\n P<\/jats:italic>\n = 0.49), and spherical equivalent (\n P<\/jats:italic>\n = 0.11). Although the corneal thickness at steep and flat meridians was not different between two groups, high-CT group had significantly thinner epithelium at inferior 2.5\u20133.5 and 3.5\u20134.5 mm zones (\n P<\/jats:italic>\n = 0.01 and 0.04) as well as superior 2.5\u20133.5 mm zone (\n P<\/jats:italic>\n = 0.03) along the steep meridian. Two groups were similar with respect to epithelial thickness of flat meridian (all\n P<\/jats:italic>\n > 0.05).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n The epithelium of steep meridian was thinner in the high-CT group compared to the low-CT group.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/joco.joco_169_23","type":"journal-article","created":{"date-parts":[[2024,10,16]],"date-time":"2024-10-16T11:04:49Z","timestamp":1729076689000},"page":"37-41","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Corneal Epithelial Thickness in Normal Corneas with Low and High Toricity"],"prefix":"10.4103","volume":"36","author":[{"given":"Amir Houshang","family":"Beheshtnejad","sequence":"first","affiliation":[{"name":"Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, 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