{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:31:02Z","timestamp":1787776262047,"version":"build-2784847793"},"reference-count":33,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To evaluate the effect of inherited retinal dystrophies (IRDs) on vision-related quality of life (VRQoL) among IRDs' patients in Iran.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This cross-sectional study was conducted on 192 patients with different types of IRDs who were randomly selected from registered patients in the Iranian National Registry for Inherited Retinal Dystrophy (IRDReg\u00ae). All ophthalmic findings were collected based on the recorded data in IRDReg\u00ae. Moreover, the eligible participants were interviewed to fill out the National Eye Institute Visual Functioning Questionnaire-25 (NEI VFQ-25) to assess their VRQoL. Ordinal logistic regression was used to evaluate the possible association of the different clinical and nonclinical factors such as demographic information, socioeconomic status, and visual function with VRQoL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The overall mean of a composite score of VRQoL was 45. All subscales obtained from the NEI VFQ-25 questionnaire except general health, mental health, and ocular pain had a significant negative correlation with logMAR best corrected visual acuity (BCVA) and near visual acuity variables. There was a statistically significant relationship between VRQoL and factors like age (odds ratio [OR] = 0.91, 95% confidence interval [CI]: 0.87\u20130.94), employment status (OR = 1.37, 95% CI: 1.05\u20134.74), logMAR BCVA (OR = 0.31, 95% CI: 0.19\u20130.49) and normal color vision (OR = 1.92, 95% CI: 1.74\u20135.01).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The VRQoL of patients with IRDs in this study was low. BCVA could be an indicator to show VRQoL.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/joco.joco_172_21","type":"journal-article","created":{"date-parts":[[2022,8,25]],"date-time":"2022-08-25T15:02:58Z","timestamp":1661439778000},"page":"80-86","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":12,"title":["Vision-Related Quality of Life in Patients with Inherited Retinal Dystrophies"],"prefix":"10.4103","volume":"34","author":[{"given":"Saeideh","family":"Shojaei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamideh","family":"Sabbaghi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yadollah","family":"Mehrabi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narsis","family":"Daftarian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koorosh","family":"Etemad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamid","family":"Ahmadieh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-12-20240910","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1167\/tvst.7.4.6","article-title":"Inherited retinal degenerations: Current landscape and knowledge gaps","volume":"7","author":"Duncan","year":"2018","journal-title":"Transl Vis Sci Technol"},{"key":"R3-12-20240910","doi-asserted-by":"crossref","first-page":"15939","DOI":"10.1038\/s41598-018-34380-0","article-title":"Relative frequency of inherited retinal dystrophies in Brazil","volume":"8","author":"Motta","year":"2018","journal-title":"Sci Rep"},{"key":"R4-12-20240910","doi-asserted-by":"crossref","first-page":"217","DOI":"10.3109\/09286586.2014.929710","article-title":"Prevalence of generalized retinal dystrophy in Denmark","volume":"21","author":"Bertelsen","year":"2014","journal-title":"Ophthalmic Epidemiol"},{"key":"R5-12-20240910","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1186\/s12886-019-1169-z","article-title":"Systematic review and meta-synthesis of coping with retinitis pigmentosa: Implications for improving quality of life","volume":"19","author":"Garip","year":"2019","journal-title":"BMC Ophthalmol"},{"key":"R6-12-20240910","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.survophthal.2004.04.003","article-title":"An overview of Leber congenital amaurosis: A model to understand human retinal development","volume":"49","author":"Koenekoop","year":"2004","journal-title":"Surv Ophthalmol"},{"key":"R7-12-20240910","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.ajo.2017.02.016","article-title":"Impact of retinitis pigmentosa on quality of life, mental health, and employment among young adults","volume":"177","author":"Chaumet-Riffaud","year":"2017","journal-title":"Am J Ophthalmol"},{"key":"R8-12-20240910","doi-asserted-by":"crossref","first-page":"631","DOI":"10.2147\/OPTH.S153754","article-title":"Clinical characteristics and causes of visual impairment in a low vision clinic in northern Jordan","volume":"12","author":"Bakkar","year":"2018","journal-title":"Clin Ophthalmol"},{"key":"R9-12-20240910","doi-asserted-by":"crossref","first-page":"6950642","DOI":"10.1155\/2017\/6950642","article-title":"Physical activity and quality of life in retinitis pigmentosa","volume":"2017","author":"Levinson","year":"2017","journal-title":"J Ophthalmol"},{"key":"R10-12-20240910","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1002\/acr.20524","article-title":"Development of a vision-related quality of life instrument for children ages 8-18 years for use in juvenile idiopathic arthritis-associated uveitis","volume":"63","author":"Angeles-Han","year":"2011","journal-title":"Arthritis Care Res (Hoboken"},{"key":"R11-12-20240910","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1007\/s10384-011-0080-9","article-title":"Relationship between vision-related quality of life and microperimetry-determined macular sensitivity in patients with retinitis pigmentosa","volume":"55","author":"Sugawara","year":"2011","journal-title":"Jpn J Ophthalmol"},{"key":"R12-12-20240910","first-page":"1496","article-title":"Psychometric properties of the National Eye Institute Visual Function Questionnaire (NEI-VFQ)","volume":"116","author":"Mangione","year":"1998","journal-title":"NEI-VFQ Field Test Investigators. 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