{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:22:42Z","timestamp":1787775762346,"version":"build-2784847793"},"reference-count":31,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To evaluate corneal endothelial health after cataract surgery without viscoelastic substance (VS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A prospective, non-randomized, case-series study was developed, and phacoemulsification cataract surgery without VS was performed on 1324 eyes between September 2015 and September 2018. As main outcomes, mean endothelial cell density (ECD) and mean central corneal thickness (CCT) were assessed before surgery and then 6 and 12 months after surgery. Data are summarized as mean, standard deviation (SD), and 95% confidence intervals (CI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      A total of 1324 eyes were operated, and 31 were excluded by intraoperative complications. The mean ECD baseline was 2506 cells\/mm\n                      <jats:sup>2<\/jats:sup>\n                      (SD = 215, CI = 2494\u20132518); 6 months after surgery, it was 2328 cells\/mm\n                      <jats:sup>2<\/jats:sup>\n                      (SD = 213, CI = 2316\u20132340); and 1 year after surgery, it was 2265 cells\/mm\n                      <jats:sup>2<\/jats:sup>\n                      (SD = 214, CI = 2253\u20132277). In terms of percentage differences, the mean ECD decrease was 9.4% after 1 year. The mean preoperative CCT was 531.6 \u03bcm (SD = 34.8, CI = 529.7\u2013533.5); 6 months after surgery, it was 537.7 \u03bcm (SD = 38.2, CI = 535.6\u2013539.8); and 1 year after surgery, it was 537.9 \u03bcm (SD = 37.9, CI = 535.8\u2013540.0). The mean CCT increased 1.2% 1 year after surgery.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Phacoemulsification cataract surgery can be completely performed without VS, with very low intraoperative complications. The postoperative ECD and CCT changes occurred primarily during the first 6 months, and the changes decreased during the second semester.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/joco.joco_185_20","type":"journal-article","created":{"date-parts":[[2024,9,10]],"date-time":"2024-09-10T15:27:18Z","timestamp":1725982038000},"page":"75-81","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":9,"title":["Corneal Endothelial Health after Phacoemulsification Cataract Surgery Without Viscoelastic Substance"],"prefix":"10.4103","volume":"33","author":[{"given":"Germ\u00e1n Roberto","family":"Bianchi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-13-20240910","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1098\/rstb.2010.0300","article-title":"The ageing lens and cataract: A model of normal and pathological ageing","volume":"366","author":"Michael","year":"2011","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"R2-13-20240910","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1007\/s00417-014-2812-2","article-title":"Aging and corneal layers: An in vivo corneal confocal microscopy study","volume":"253","author":"Gambato","year":"2015","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"R3-13-20240910","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1097\/ICU.0000000000000121","article-title":"Advances in cataract surgery: Preserving the corneal endothelium","volume":"26","author":"Ho","year":"2015","journal-title":"Curr Opin Ophthalmol"},{"key":"R4-13-20240910","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/j.jcrs.2016.02.039","article-title":"Nanosecond laser-assisted cataract surgery: Endothelial cell study","volume":"42","author":"Tanev","year":"2016","journal-title":"J Cataract Refract Surg"},{"key":"R5-13-20240910","doi-asserted-by":"crossref","first-page":"658","DOI":"10.5301\/ejo.5000251","article-title":"Endothelial cells and central corneal thickness after modified sutureless manual small-incision cataract surgery","volume":"23","author":"Goldenberg","year":"2013","journal-title":"Eur J Ophthalmol"},{"key":"R6-13-20240910","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1001\/jamaophthalmol.2013.5009","article-title":"Phacopower modulation and the risk for postoperative corneal decompensation: A randomized clinical trial","volume":"131","author":"Doors","year":"2013","journal-title":"JAMA Ophthalmol"},{"key":"R7-13-20240910","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/S0886-3350(13)80228-3","article-title":"Effect of two anterior capsulotomy techniques on the corneal endothelium","volume":"20","author":"Padmanabhan","year":"1994","journal-title":"J Cataract Refract Surg"},{"key":"R8-13-20240910","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/S0886-3350(98)80049-7","article-title":"Endothelial damage with cataract surgery techniques","volume":"24","author":"D\u00edaz-Valle","year":"1998","journal-title":"J Cataract Refract Surg"},{"key":"R9-13-20240910","first-page":"23","article-title":"Phaco-emulsification and aspiration","volume":"64","author":"Kelman","year":"1967","journal-title":"A new technique of cataract removal. 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