{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:32:41Z","timestamp":1787758361419,"version":"build-2784847793"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To study the effect of intraocular pressure (IOP) on refractive outcomes after deep anterior lamellar keratoplasty (DALK).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This retrospective study included eyes which underwent DALK. DALK technique involved either modified Anwar big-bubble if possible or manual anterior lamellar dissection. Our main outcome measures are postoperative IOP and refractive outcomes at postoperative week and months 1, 3, 6, and 12.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Fifty-nine eyes of 59 patients were included. DALK was performed for optical (93.2%) and tectonic (6.8%) purposes. 76.3% of the patients had keratoconus. Anwar's big-bubble technique was successful in 30 cases. Linear mixed-model was used to analyze the effect of the highest postoperative IOP measured prior to measurement of postoperative cylinder. Patients with greater maximum postoperative IOP measured had worse postoperative cylinder (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.015) and spherical equivalent (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.012). Those with IOP more than 21 mmHg had worse postoperative cylinder (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.050) and spherical equivalent (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.054). The method of DALK and presence of suture removal were not shown to statistically affect postoperative cylinder.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Our study shows a positive correlation between postoperative IOP and worse spherical equivalent and cylinder post-DALK, emphasizing the need for good IOP control with IOP-lowering medication(s).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/joco.joco_211_21","type":"journal-article","created":{"date-parts":[[2022,8,25]],"date-time":"2022-08-25T15:02:58Z","timestamp":1661439778000},"page":"30-36","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Relationship Between Postoperative Intraocular Pressure and Refractive Outcomes in Patients after Deep Anterior Lamellar Keratoplasty"],"prefix":"10.4103","volume":"34","author":[{"given":"Dayna Yong","family":"Wei Wei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ray","family":"Manotosh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna Tan","family":"Wee Tien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charmaine Chai","family":"Hui-Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-4-20240910","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1016\/j.ajo.2015.07.005","article-title":"Factors predicting refractive outcomes after deep anterior lamellar keratoplasty in keratoconus","volume":"160","author":"Feizi","year":"2015","journal-title":"Am J Ophthalmol"},{"key":"R3-4-20240910","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1016\/S0140-6736(12)60437-1","article-title":"Corneal transplantation","volume":"379","author":"Tan","year":"2012","journal-title":"Lancet"},{"key":"R4-4-20240910","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.ajo.2016.07.025","article-title":"Incidence and risk factors of elevated intraocular pressure following deep anterior lamellar keratoplasty","volume":"170","author":"Huang","year":"2016","journal-title":"Am J Ophthalmol"},{"key":"R5-4-20240910","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1038\/sj.eye.6702136","article-title":"Corneal topographic response to intraocular pressure reduction in patients with vernal keratoconjunctivitis and steroid-induced glaucoma","volume":"21","author":"Dada","year":"2007","journal-title":"Eye (Lond"},{"key":"R6-4-20240910","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1111\/j.1755-3768.1988.tb02685.x","article-title":"Progressive myopia and intraocular pressure: What is the linkage? 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