{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T16:22:37Z","timestamp":1787847757712,"version":"build-2784847793"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To evaluate the effects of a fish oil-containing regimen on the severity of retinopathy of prematurity (ROP) in preterm infants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>In this retrospective, observational study, 82 preterm infants with documented retinal examinations were evaluated. Patients' demographic data, associated morbidities, the worst ROP zone, stage, and the presence of plus disease during the follow-up examinations, and the need for ROP treatment in the two groups were recorded and analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Forty-three infants were treated with INTRAlipid\u00ae, and 39 infants were treated with 20% SMOFlipid. There were no differences in gestational age, birth weight, and associated morbidities between the two groups. No differences were observed among the two groups in their need for treatment (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.51), ROP zones (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.62), and plus disease (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.38). Although no difference was seen in ROP stages between the groups (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.41), in subgroup analysis, Stage 3 (severe ROP) occurred significantly lower in the SMOFlipid group (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.04) and Stage 0 occurred significantly higher in the SMOFlipid-treated infants (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>This study showed no difference between the two groups regarding the need for the treatment. The lower prevalence of severe ROP in preterm infants receiving SMOFlipid emulsion was observed comparing to the INTRAlipid-treated infants.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/joco.joco_23_20","type":"journal-article","created":{"date-parts":[[2021,1,11]],"date-time":"2021-01-11T05:29:44Z","timestamp":1610342984000},"page":"69-74","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":7,"title":["Parenteral Fish-Oil Lipid Emulsions in Retinopathy of Prematurity"],"prefix":"10.4103","volume":"32","author":[{"given":"Golnaz","family":"Gharehbaghi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parisa","family":"Mohagheghi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahad","family":"Sedaghat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamid","family":"Riazi-Esfahani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masoud","family":"Mirghorbani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nastaran","family":"Khosravi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-10-20240910","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.jaapos.2012.09.004","article-title":"An update on progress and the changing epidemiology of causes of childhood blindness worldwide","volume":"16","author":"Kong","year":"2012","journal-title":"J AAPOS"},{"key":"R2-10-20240910","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.ophtha.2014.07.050","article-title":"Pathophysiology and mechanisms of severe retinopathy of prematurity","volume":"122","author":"Hartnett","year":"2015","journal-title":"Ophthalmology"},{"key":"R3-10-20240910","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1177\/0884533612439896","article-title":"A.S.P.E.N. position paper: Clinical role for alternative intravenous fat emulsions","volume":"27","author":"Vanek","year":"2012","journal-title":"Nutr Clin Pract"},{"key":"R4-10-20240910","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1093\/ajcn\/82.2.281","article-title":"Is docosahexaenoic acid, an n-3 long-chain polyunsaturated fatty acid, required for development of normal brain function? 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