{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:24:42Z","timestamp":1787840682022,"version":"build-2784847793"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To determine the short-term outcomes of a modified Moorfields Safer Surgery System technique of trabeculectomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This is a prospective interventional study. Trabeculectomy was performed according to the author\u2019s modification of Moorfields Safer Surgery System. This method allows titrating the opening pressure of trabeculectomy by varying the side cuts, varying the ostium size, and adjusting the tightness of the sutures. Forty-four eyes of 43 patients were included. Main outcome measures include postoperative intraocular pressure (IOP), incidence of intra and postoperative complications, and success up to 6 months after surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The mean preoperative and postoperative IOP at 6 months were 20.97 \u00b1 7.93 mmHg and 12.69 \u00b1 4.76 mmHg, respectively (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 44). 70.5% of the patients had absolute success at 6 months, and the overall success was 88.6%. None of the patients had hypotony and there were no intraoperative complications noted. Forty-two out of 44 eyes (95.5%) had diffuse formed blebs without leak on the 1\n                      <jats:sup>st<\/jats:sup>\n                      postoperative day. The most common postoperative complication (13.6%) was a conjunctival leak that was detected on fluorescein staining. In all these patients, the anterior chamber was deep, and the bleb well formed. These leaks were resolved with conservative measures. Many of these leaks would have been missed if not intentionally looked for. Excluding this complication, we had a complication rate of 9.1%.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The authors\u2019 modification of the Moorfields Safer Surgery System technique may allow the surgeon to optimize aqueous flow through trabeculectomy while mitigating complications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/joco.joco_241_23","type":"journal-article","created":{"date-parts":[[2024,10,16]],"date-time":"2024-10-16T11:04:40Z","timestamp":1729076680000},"page":"23-30","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Short-Term Outcomes of a Modified Safer Surgery Trabeculectomy Technique"],"prefix":"10.4103","volume":"36","author":[{"given":"Prakriti Yagnam","family":"Konuganti","sequence":"first","affiliation":[{"name":"Department of Glaucoma, The Eye Foundation, Coimbatore, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muralidhar","family":"Rajamani","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, The Eye Foundation, Coimbatore, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig John","family":"Chaya","sequence":"additional","affiliation":[{"name":"Moran Eye Centre, Salt Lake City, Utah, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chitra","family":"Ramamurthy","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, The Eye Foundation, Coimbatore, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,10,16]]},"reference":[{"key":"R1-20241018","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1038\/eye.2009.132","article-title":"Combined cataract and trabeculectomy surgery for advanced glaucoma in East Africa;visual and intra-ocular pressure outcomes","volume":"24","author":"Bowman","year":"2010","journal-title":"Eye (Lond)"},{"key":"R2-20241018","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/0002-9394(68)91288-9","article-title":"Trabeculectomy. 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trabeculectomy leakage:Incidence, time course, severity, and impact on surgical outcome","volume":"88","author":"Henderson","year":"2004","journal-title":"Br J Ophthalmol"},{"key":"R14-20241018","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1097\/IJG.0000000000000726","article-title":"Intermediate term outcomes of early posttrabeculectomy bleb leaks managed by large diameter soft bandage contact lens","volume":"26","author":"Gollakota","year":"2017","journal-title":"J Glaucoma"},{"key":"R15-20241018","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1038\/eye.1993.23","article-title":"Is high initial aqueous outflow of benefit in trabeculectomy?","volume":"7","author":"Batterbury","year":"1993","journal-title":"Eye (Lond)"},{"key":"R16-20241018","doi-asserted-by":"crossref","first-page":"849","DOI":"10.2147\/OPTH.S192044","article-title":"Evaluating the efficacy of short duration Mitomycin C in safe surgery system trabeculectomy combined with cataract 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