{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T17:12:49Z","timestamp":1786122769133,"version":"build-2736575974"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To describe a novel technique for repairing large iris defects using an allogenic corneal iris segment (ACIS), referred to as the Antep procedure, and to present its application in two challenging clinical cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Two cases with significant iris loss and photic symptoms underwent ACIS implantation. The ACIS was shaped into a crescent-shaped segment specifically designed to cover the iris defect and stained with trypan blue. It was then positioned in the anterior chamber and secured with three-point fixation at the nasal and temporal positions to the residual iris and superiorly to the sclera.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>In both patients, ACIS implantation provided effective anatomical reconstruction of the iris defect and led to meaningful functional improvement, particularly in photic symptoms. The segments remained well positioned throughout follow-up, and no intraoperative or postoperative complications were observed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The Antep procedure offers a biologically integrated, low-cost, and technically feasible option for reconstruction of large iris defects. Further studies with longer follow-up are warranted to evaluate long-term outcomes and broader applicability.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/joco.joco_321_25","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T14:39:21Z","timestamp":1786027161000},"page":"96-101","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Allogenic Corneal Iris Segment Implantation for Repair of Large Iris Defect: The Antep Procedure"],"prefix":"10.4103","volume":"38","author":[{"given":"Necip","family":"Kara","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elif Sarsu","family":"Kocaaslan","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eren","family":"Arslan","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,8,6]]},"reference":[{"key":"R1-20260807","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1007\/s00417-016-3292-3","article-title":"Long-term results after artificial iris implantation in patients with aniridia","volume":"254","author":"Rickmann","year":"2016","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"R2-20260807","doi-asserted-by":"crossref","first-page":"506","DOI":"10.5301\/ejo.5000922","article-title":"Single-pass four-throw technique for pupilloplasty","volume":"27","author":"Narang","year":"2017","journal-title":"Eur J 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