{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T17:13:48Z","timestamp":1786122828255,"version":"build-2736575974"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"Abstract<\/jats:title>\n \n Purpose:<\/jats:title>\n To investigate the prevalence, clinical course, and prognostic significance of hyporeflective micro-elevations and irregularity of the ellipsoid zone (MEEZ) in blunt ocular trauma.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n Patients with blunt ocular trauma underwent standard ophthalmological examination and optical coherence tomography angiography. MEEZ was defined as small hyporeflective foci at the level of the ellipsoid and interdigitation zone, with disappearance of the thin hyporeflective band between these layers. The prevalence and spatial distribution of MEEZ, choriocapillaris perfusion, and associated findings were evaluated.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n MEEZ was identified in 62 (40.3%) out of 154 eyes with blunt trauma, including nine eyes with MEEZ as the only form of posterior segment injury, and 53 eyes where MEEZ was found with other posterior segment injuries. Mean best-corrected visual acuity in eyes with MEEZ only was 0.0 logMAR (20\/20 of Snellen equivalent). In eyes where MEEZ was associated with other posterior segment injuries, mean best-corrected visual acuity was 0.9 \u00b1 0.64 logMAR (approximately 20\/160 of Snellen equivalent). Choriocapillaris perfusion area in eyes with MEEZ only and healthy fellow eyes was 21.1 \u00b1 1.3 and 20.4 \u00b1 1.2 mm\n 2<\/jats:sup>\n (\n P<\/jats:italic>\n > 0.05), respectively. During the follow-up, MEEZ showed complete resolution in all cases with available follow-up data (\n n<\/jats:italic>\n = 15) after a median period of 34.0 days.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions:<\/jats:title>\n MEEZ is an important part of the spectrum of traumatic retinal changes frequently observed in blunt ocular trauma. As the only manifestation of blunt ocular trauma, MEEZ is associated with a favorable prognosis.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/joco.joco_51_26","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T14:42:30Z","timestamp":1786027350000},"page":"72-78","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Traumatic Hyporeflective Micro-Elevations and Irregularity of the Ellipsoid Zone in Blunt Ocular Trauma"],"prefix":"10.4103","volume":"38","author":[{"given":"Ekaterina K.","family":"Gladisheva","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Military Medical Academy, St. Petersburg, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexey N.","family":"Kulikov","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Military Medical Academy, St. Petersburg, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dmitrii S.","family":"Maltsev","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Military Medical Academy, St. Petersburg, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,8,6]]},"reference":[{"key":"R1-20260807","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1136\/bjophthalmol-2020-317422","article-title":"Central serous chorioretinopathy imaging biomarkers","volume":"106","author":"Singh","year":"2022","journal-title":"Br J Ophthalmol"},{"key":"R2-20260807","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/j.survophthal.2023.03.003","article-title":"Foveal photoreceptor disruption in ocular diseases: An optical coherence tomography-based differential diagnosis","volume":"68","author":"Singh","year":"2023","journal-title":"Surv Ophthalmol"},{"key":"R3-20260807","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.oret.2020.09.018","article-title":"Outer foveal microdefects","volume":"5","author":"Cohen","year":"2021","journal-title":"Ophthalmol Retina"},{"key":"R4-20260807","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.survophthal.2016.03.003","article-title":"Acute macular neuroretinopathy: A comprehensive review of the literature","volume":"61","author":"Bhavsar","year":"2016","journal-title":"Surv Ophthalmol"},{"key":"R5-20260807","doi-asserted-by":"crossref","first-page":"566","DOI":"10.4103\/ijo.IJO_1251_18","article-title":"Acute macular neuroretinopathy after blunt ocular trauma: A rare association","volume":"67","author":"Mishra","year":"2019","journal-title":"Indian J Ophthalmol"},{"key":"R6-20260807","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.jcjo.2020.06.020","article-title":"Hyporeflective micro-elevations and irregularity of the ellipsoid layer: Novel optical coherence tomography features in commotio retinae","volume":"55","author":"Venkatesh","year":"2020","journal-title":"Can J Ophthalmol"},{"key":"R7-20260807","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1016\/j.ajo.2013.06.023","article-title":"Optical coherence tomography morphologic grading of macular commotio retinae and its association with anatomic and visual outcomes","volume":"156","author":"Ahn","year":"2013","journal-title":"Am J Ophthalmol"},{"key":"R8-20260807","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1001\/jamaophthalmol.2016.0502","article-title":"Quantification of ellipsoid zone changes in retinitis pigmentosa using en face spectral domain-optical coherence tomography","volume":"134","author":"Hariri","year":"2016","journal-title":"JAMA Ophthalmol"},{"key":"R9-20260807","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.ajo.2021.10.012","article-title":"Longitudinal assessment of ellipsoid zone recovery using en face optical coherence tomography after retinal detachment repair","volume":"236","author":"Figueiredo","year":"2022","journal-title":"Am J Ophthalmol"},{"key":"R10-20260807","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1097\/00006982-199212010-00006","article-title":"Histopathology of commotio retinae","volume":"12","author":"Mansour","year":"1992","journal-title":"Retina"},{"key":"R11-20260807","doi-asserted-by":"crossref","first-page":"2267","DOI":"10.1001\/archopht.1978.03910060563021","article-title":"Traumatic retinopathy in primates. The explanation of commotio retinae","volume":"96","author":"Sipperley","year":"1978","journal-title":"Arch Ophthalmol"},{"key":"R12-20260807","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.ajo.2020.09.003","article-title":"Multimodal imaging features and clinical relevance of subretinal lipid globules","volume":"222","author":"Fern\u00e1ndez-Avellaneda","year":"2021","journal-title":"Am J Ophthalmol"},{"key":"R13-20260807","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1016\/j.ophtha.2014.02.023","article-title":"Proposed lexicon for anatomic landmarks in normal posterior segment spectral-domain optical coherence tomography: The IN\u2022OCT consensus","volume":"121","author":"Staurenghi","year":"2014","journal-title":"Ophthalmology"},{"key":"R14-20260807","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1097\/IAE.0b013e318227fd01","article-title":"Spectral-domain optical coherence tomography in patients with commotio retinae","volume":"32","author":"Souza-Santos","year":"2012","journal-title":"Retina"},{"key":"R15-20260807","doi-asserted-by":"crossref","first-page":"2471","DOI":"10.1007\/s00417-024-06436-7","article-title":"Optical coherence tomography angiography suggests choriocapillaris perfusion deficit as etiology of acute macular neuroretinopathy","volume":"262","author":"von der Burchard","year":"2024","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"R16-20260807","doi-asserted-by":"crossref","first-page":"691","DOI":"10.2147\/RMHP.S505657","article-title":"Epidemiology of ocular trauma and predictive modeling of visual outcomes: A 12-year retrospective study at a tertiary hospital in China","volume":"18","author":"Lu","year":"2025","journal-title":"Risk Manag Healthc Policy"},{"key":"R17-20260807","doi-asserted-by":"crossref","first-page":"2196","DOI":"10.1016\/S0161-6420(00)00390-0","article-title":"The prevalence and 5-year incidence of ocular trauma. The beaver dam eye study","volume":"107","author":"Wong","year":"2000","journal-title":"Ophthalmology"}],"container-title":["Journal of Current Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/joco.joco_51_26","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T12:00:49Z","timestamp":1786104049000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/joco.joco_51_26"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/joco.joco_51_26","relation":{},"ISSN":["2452-2325"],"issn-type":[{"value":"2452-2325","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2026-02-18","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-07","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}