{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:45:33Z","timestamp":1787071533174,"version":"build-2736575974"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 1","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:p>McCune-Albright Syndrome (MAS) is a rare disorder characterized by the combination of two or more classic features: Fibrous dysplasia of bone, caf\u00e9-au-lait skin macules and hyperfunctioning endocrinopathies. Bisphosphonates are commonly administered in these patients to mitigate bone lesions and relieve pain; despite the benefits of this medication, its use places patients at risk for medication-related osteonecrosis of the jaws (MRONJ) making it essential to obtain a thorough medical history prior to any oral surgical procedure. The aim of this study was to present a rare case of MRONJ in a 29-year-old female patient with MAS, who had been receiving intravenous zoledronate for seven years and was submitted to the upper right impacted third molar removal. MRONJ remains a challenging condition with no standardized treatment protocol. In the present case, bone sequestrum removal combined with Platelet-Rich Fibrin and buccal fat pad grafting, along with pentoxifylline and tocopherol therapy, yielded positive outcomes.<\/jats:p>","DOI":"10.4103\/jomfp.jomfp_124_25","type":"journal-article","created":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T10:00:25Z","timestamp":1764324025000},"page":"S44-S48","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Medication-related osteonecrosis of the jaw in patient with McCune-Albright syndrome: A rare case report"],"prefix":"10.4103","volume":"29","author":[{"given":"Cintia Mussi","family":"Milani","sequence":"first","affiliation":[{"name":"Faculty of Dentistry, Universidade Tuiuti do Paran\u00e1, Curitiba, Paran\u00e1, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guilherme Vargas","family":"Marques","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry, 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