{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:03:39Z","timestamp":1787169819325,"version":"build-2736575974"},"reference-count":5,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>An 18-year-old male presented with a 3-week history of progressively enlarging nodular growth in the posterior right mandibular region. The patient denied the use of tobacco in any form or history of trauma, and his family history was unremarkable. Clinical examination revealed a 2 \u00d7 3 cm reddish-pink, firm lesion with palpable submandibular lymph nodes. Radiological imaging showed a well-defined radiolucency distal to tooth #47. An incisional biopsy revealed the proliferation of spindle cells and ameloblastomatous epithelium showing features like pleomorphism, cellular crowding, and mitotic figures. Immunohistochemical analysis confirmed odontogenic origin. Based on the above findings, the diagnosis of the spindle cell variant of ameloblastic carcinoma (AC) was rendered. AC, constituting less than 2% of odontogenic tumours, and the spindle cell variant, a rare subtype with fewer than 15 reported cases, pose diagnostic challenges, necessitating careful histopathological and immunohistochemical evaluation for accurate diagnosis and treatment planning.<\/jats:p>","DOI":"10.4103\/jomfp.jomfp_272_24","type":"journal-article","created":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T08:00:26Z","timestamp":1735632026000},"page":"713-715","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Spindle cell variant of ameloblastic carcinoma: A diagnostic challenge"],"prefix":"10.4103","volume":"28","author":[{"given":"Mamata S.","family":"Kamat","sequence":"first","affiliation":[{"name":"Department of Oral Pathology and Microbiology, Bharati Vidyapeeth (Deemed to be University), Dental College and Hospital, Sangli, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uma V.","family":"Datar","sequence":"additional","affiliation":[{"name":"Department of Oral Pathology and Microbiology, Bharati Vidyapeeth (Deemed to be University), Dental College and Hospital, Sangli, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay S.","family":"Byakodi","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Bharati Vidyapeeth (Deemed to be University), Dental College and Hospital, Sangli, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit A.","family":"Basannavar","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Bharati Vidyapeeth (Deemed to be University), Dental College and Hospital, Sangli, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,12,31]]},"reference":[{"key":"R1-20250108","doi-asserted-by":"crossref","first-page":"4191","DOI":"10.1002\/hed.25926","article-title":"Ameloblastic carcinoma: Clinicopathological analysis of 18 cases and a systematic review","volume":"41","author":"Deng","year":"2019","journal-title":"Head Neck"},{"key":"R3-20250108","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.ajoms.2021.02.017","article-title":"Spindle cell variant of ameloblastic carcinoma: An autopsy case of extensive distant metastases","volume":"33","author":"Takahata","year":"2021","journal-title":"J Oral Maxillofac Surg Med Pathol"},{"key":"R4-20250108","doi-asserted-by":"crossref","first-page":"e614","DOI":"10.7205\/MILMED-D-14-00509","article-title":"Spindle cell variant of ameloblastic carcinoma: A case report and review of literature","volume":"180","author":"McNaught","year":"2015","journal-title":"Mil Med"},{"key":"R5-20250108","doi-asserted-by":"crossref","first-page":"e54","DOI":"10.1016\/j.oooo.2015.06.034","article-title":"Spindle cell variant of ameloblastic carcinoma: A case report and literature review","volume":"121","author":"Matsushita","year":"2016","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"R6-20250108","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.coms.2004.03.009","article-title":"Odontogenic malignancies","volume":"16","author":"Slater","year":"2004","journal-title":"Oral Maxillofac Surg Clin North Am"}],"container-title":["Journal of Oral and Maxillofacial Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jomfp.jomfp_272_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:13:02Z","timestamp":1787166782000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jomfp.jomfp_272_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":5,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jomfp.jomfp_272_24","relation":{},"ISSN":["0973-029X","1998-393X"],"issn-type":[{"value":"0973-029X","type":"print"},{"value":"1998-393X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"2024-09-16","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-05","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}