{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:42:11Z","timestamp":1786653731054,"version":"build-2736575974"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Oral submucous fibrosis (OSF) has one of the highest malignant transformation rates among all potentially malignant disorders. An early diagnosis and staging of the condition with the help of clinical findings may help in the improvement of the prognosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>To evaluate the correlation of stages of OSF based on mouth opening with the presence of blanching, fibrous bands, and shape of the uvula.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>A retrospective, observational study was conducted in the Department of Oral Medicine and Radiology, and 1,267 case records were included in the study after the evaluation of patient data. Changes in mouth opening, fibrosis, blanching, and uvula were noted and analyzed using the Chi-square test.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The highest incidence of fibrous bands and blanching was seen on buccal mucosa in Group C. Blanching ranged from 65% to 93% in all stages of the disease, and blanching on the palate was seen to be the highest in Group A. The percentage of Group D patients with deviated uvula (26%) was lower than that of Group A patients (38%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Clinical findings like the fibrous bands, blanching, and deviation of the uvula contribute to the assessment of severity of the disease, and grading OSF only based on mouth opening, though simple and convenient, might inadequately represent the disease severity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jomfp.jomfp_27_24","type":"journal-article","created":{"date-parts":[[2025,3,30]],"date-time":"2025-03-30T12:33:29Z","timestamp":1743338009000},"page":"54-60","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Correlation of blanching, fibrosis, and uvular changes with the extent of mouth opening in oral submucous fibrosis \u2013 A 9-year retrospective analysis"],"prefix":"10.4103","volume":"29","author":[{"given":"Sneha R.","family":"Sharma","sequence":"first","affiliation":[{"name":"Department of Oral Medicine and Radiology, Pacific Dental College and Hospital, Udaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samiksha","family":"Chavan","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Government Dental College and Hospital, Aurangabad, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Freny R.","family":"Karjodkar","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Nair Hospital Dental College, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaustubh","family":"Sansare","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Nair Hospital Dental College, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prajakta","family":"Khelkar","sequence":"additional","affiliation":[{"name":"Department of Dentistry, Government Medical College and Hospital, Chandrapur, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aswathi","family":"Unnikrishnan","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Nair Hospital Dental College, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,3,28]]},"reference":[{"key":"R1-20250328","doi-asserted-by":"crossref","first-page":"89","DOI":"10.4103\/njms.NJMS_32_17","article-title":"Oral submucous fibrosis: Newer proposed classification with critical updates in pathogenesis and management strategies","volume":"8","author":"Passi","year":"2017","journal-title":"Natl J Maxillofac Surg"},{"key":"R2-20250328","doi-asserted-by":"crossref","first-page":"216","DOI":"10.15430\/JCP.2015.20.3.216","article-title":"Association between grading of oral submucous fibrosis with frequency and consumption of areca nut and its derivatives in a wide age group: A Multi-centric cross sectional study from Karachi, Pakistan","volume":"20","author":"Hosein","year":"2015","journal-title":"J Cancer Prev"},{"key":"R3-20250328","doi-asserted-by":"crossref","first-page":"2940","DOI":"10.3390\/ijms20122940","article-title":"Oral submucous fibrosis: A review on etiopathogenesis, diagnosis, and therapy","volume":"20","author":"Shih","year":"2019","journal-title":"Int J Mol Sci"},{"key":"R4-20250328","doi-asserted-by":"crossref","first-page":"193","DOI":"10.2147\/CCID.S80576","article-title":"Oral submucous fibrosis: An update","volume":"8","author":"Wollina","year":"2015","journal-title":"Clin Cosmet Investig Dermatol"},{"key":"R5-20250328","doi-asserted-by":"crossref","first-page":"216","DOI":"10.5466\/ijoms.10.216","article-title":"Clinical staging of oral submucous fibrosis: A review","volume":"10","author":"Shivakumar","year":"2011","journal-title":"Int J Oral Med Sci"},{"key":"R6-20250328","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s40463-020-0399-7","article-title":"Oral submucous fibrosis: A contemporary narrative review with a proposed inter-professional approach for an early diagnosis and clinical management","volume":"49","author":"Rao","year":"2020","journal-title":"J Otolaryngol Head Neck Surg"},{"key":"R7-20250328","doi-asserted-by":"crossref","first-page":"154","DOI":"10.4103\/0973-029X.84481","article-title":"Clinical and histopathological evaluation of collagen fiber orientation in patients with oral submucous fibrosis","volume":"15","author":"Smitha","year":"2011","journal-title":"J Oral Maxillofac Pathol"},{"key":"R8-20250328","doi-asserted-by":"crossref","first-page":"623","DOI":"10.4103\/ijdr.IJDR_275_16","article-title":"Velar morphological variants in oral submucous fibrosis: A comparative digital cephalometric study","volume":"28","author":"Patil","year":"2017","journal-title":"Indian J Dent Res"},{"key":"R9-20250328","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1111\/j.1601-0825.2009.01578.x","article-title":"Uvular abnormalities in patients with submucous fibrosis","volume":"15","author":"Chaturvedi","year":"2009","journal-title":"Oral Dis"},{"key":"R10-20250328","doi-asserted-by":"crossref","first-page":"84","DOI":"10.4103\/0970-4388.26022","article-title":"Epidemiological and etiological study of oral submucous fibrosis among gutkha chewers of Patna, Bihar, India","volume":"24","author":"Ahmad","year":"2006","journal-title":"J Indian Soc Pedod Prev Dent"},{"key":"R11-20250328","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.jobcr.2013.10.005","article-title":"Prevalence of oral submucous fibrosis among habitual gutkha and areca nut chewers in Moradabad district","volume":"4","author":"Nigam","year":"2014","journal-title":"J Oral Biol Craniofac Res"},{"key":"R12-20250328","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1054\/bjom.1999.0062","article-title":"Clinical and functional staging of oral submucous fibrosis","volume":"38","author":"Haider","year":"2000","journal-title":"Br J Oral Maxillofac Surg"},{"key":"R13-20250328","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1259\/dmfr\/55898096","article-title":"Morphological variety of the soft palate in normal individuals: A digital cephalometric study","volume":"37","author":"You","year":"2008","journal-title":"Dentomaxillofac Radiol"},{"key":"R14-20250328","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1111\/j.1600-0714.1995.tb01209.x","article-title":"Clinical evaluation of different treatment methods for oral submucous fibrosis. A 10-year experience with 150 cases","volume":"24","author":"Lai","year":"1995","journal-title":"J Oral Pathol Med"},{"key":"R15-20250328","doi-asserted-by":"crossref","first-page":"2612","DOI":"10.4103\/jfmpc.jfmpc_465_19","article-title":"Prevalence of oral submucous fibrosis in patients visiting dental OPD of a dental college in Kanpur: A demographic study","volume":"8","author":"Srivastava","year":"2019","journal-title":"J Family Med Prim Care"},{"key":"R16-20250328","doi-asserted-by":"crossref","first-page":"124","DOI":"10.4103\/0972-1363.195085","article-title":"Oral submucous fibrosis: A demographic study","volume":"28","author":"Kumar","year":"2016","journal-title":"J Indian Acad Oral Med Radiol"},{"key":"R17-20250328","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/1758-3284-1-10","article-title":"Correlation of histopathological diagnosis with habits and clinical findings in oral submucous fibrosis","volume":"1","author":"Pandya","year":"2009","journal-title":"Head Neck Oncol"},{"key":"R18-20250328","first-page":"111","article-title":"Comparative study of clinical staging of oral submucous fibrosis with qualitative analysis of collagen fibers under polarized microscopy","volume":"10","author":"Modak","year":"2015","journal-title":"Iran J Pathol"},{"key":"R19-20250328","first-page":"789","article-title":"Submucous fibrosis of the oral cavity. 1. Clinical features","volume":"35","author":"Wahi","year":"1966","journal-title":"Bull World Health Organ"},{"key":"R20-20250328","doi-asserted-by":"crossref","first-page":"363","DOI":"10.4103\/jispcd.JISPCD_92_19","article-title":"Oral submucous fibrosis: Correlation of clinical grading to various habit factors","volume":"9","author":"Jha","year":"2019","journal-title":"J Int Soc Prev Community Dent"},{"key":"R21-20250328","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/S0901-5027(05)80473-4","article-title":"Oral submucous fibrosis: a new concept in surgical management. Report of 100 cases","volume":"24","author":"Khanna","year":"1995","journal-title":"Int J Oral Maxillofac Surg"}],"container-title":["Journal of Oral and Maxillofacial Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jomfp.jomfp_27_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:41:32Z","timestamp":1786650092000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jomfp.jomfp_27_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jomfp.jomfp_27_24","relation":{},"ISSN":["0973-029X","1998-393X"],"issn-type":[{"value":"0973-029X","type":"print"},{"value":"1998-393X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2024-01-29","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-03","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}